Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2A (GRIN2A) and GluN3A (GRIN3A)

Stable Identifier
R-HSA-9610270
Type
Reaction [binding]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
ReviewStatus
5/5
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Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2A (GRIN2A) and GluN3A (GRIN3A)
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GluN1 (GRIN1) binds to GluN2A (GRIN2A) and GluN3A (GRIN3A) to form a tri-heteromeric GluN1:GluN2A:GluN3A (GRIN1:GRIN2A:GRIN3A) NMDA receptor (Perez-Otano et al. 2001, Nilsson et al. 2007, Tong et al. 2008).
Literature References
PubMed ID Title Journal Year
17997397 Analysis of NR3A receptor subunits in human native NMDA receptors

Samuelsson, EB, Nilsson, A, Muly, EC, Sundström, E, Eriksson, M, Benedikz, E, Bogdanovic, N, Akesson, E

Brain Res. 2007
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Formation of tri-heterotetramers of GluN1 (Grin1), GluN2A (Grin2a) and GluN3A (Grin3a) (Rattus norvegicus)
Authored
Orlic-Milacic, M  (2019-01-05)
Reviewed
Traynelis, SF  (2019-02-11)
Camp, C  (2019-02-11)
Bhattacharya, S  (2019-02-11)
Created
Orlic-Milacic, M  (2018-06-06)
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