GluN2A (GRIN2A) forms a di-heterotetramer with GluN1 (GRIN1). Based on the crystal structure of the rat GluN1:GluN2A (Grin1:Grin2a) NMDA receptor (Furukawa et al. 2005) and the Cryo-EM structure of the human GluN1:GluN2A (GRIN1:GRIN2A) NMDA receptor (Zhang et al. 2018), the tetramer includes 2 molecules of GluN1 and two molecules of GluN2A. GluN2A expression starts postnatally and GluN2A is highly expressed in adult brain (Monyer et al. 1992, Sheng et al. 1994).
Zhang, JB, Chang, S, Xu, P, Miao, M, Wu, H, Zhang, Y, Zhang, T, Wang, H, Zhang, J, Xie, C, Song, N, Luo, C, Zhang, X, Zhu, S
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