NICD4 binds to TACC3

Stable Identifier
R-HSA-9604675
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Based on studies in mice, the intracellular domain of NOTCH4, NICD4, binds to transforming acidic coiled-coil protein-3 (TACC3). TACC3 is implicated as a negative regulator of NOTCH4 signaling and may compete with NICD4 binding to RBPJ (Bargo et al. 2010).

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