Reactome | NOTCH4 binds FLT4 gene promoter

NOTCH4 binds FLT4 gene promoter

Stable Identifier

R-HSA-9604451

Type

Reaction [binding]

Species

Homo sapiens

Compartment

nucleoplasm

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The NOTCH4 coactivator complex, composed of NICD4 (NOTCH4 intracellular domain fragment), RBPJ (CSL) and one of mastermind proteins, MAML1, MAML2 or MAML3, binds to CSL response elements in the promoter of the FLT4 (VEGFR3) gene, encoding Vascular endothelial growth factor receptor-3 (Shawber et al. 2007).

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