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PTPRO [plasma membrane]
Stable Identifier
R-HSA-9603761
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Receptor-type tyrosine-protein phosphatase O
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by NTRKs (Homo sapiens)
Signaling by NTRK3 (TRKC) (Homo sapiens)
Protein tyrosine phosphatases dephosphorylate NTRK3 (Homo sapiens)
(PTPRO,PTPRS) [plasma membrane] (Homo sapiens)
PTPRO [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q16827 PTPRO
Gene Names
PTPRO, GLEPP1, PTPU2
Chain
signal peptide:1-29, chain:30-1216
Reference Genes
BioGPS Gene:5800 PTPRO
COSMIC (genes):PTPRO PTPRO
CTD Gene:5800 PTPRO
dbSNP Gene:5800 PTPRO
ENSEMBL:ENSG00000151490 PTPRO
ENSEMBL_homo_sapiens_GENE:ENSG00000151490.15 PTPRO
HGNC:9678 PTPRO
KEGG Gene (Homo sapiens):5800 PTPRO
Monarch:5800 PTPRO
NCBI Gene:5800 PTPRO
OMIM:600579 PTPRO
UCSC:Q16827 PTPRO
Reference Transcript
RefSeq:NM_030667.2 PTPRO
RefSeq:NM_030669.2 PTPRO
RefSeq:NM_030671.2 PTPRO
RefSeq:NM_002848.3 PTPRO
RefSeq:NM_030668.2 PTPRO
RefSeq:NM_030670.2 PTPRO
Other Identifiers
11725684_a_at
11725685_a_at
11725686_a_at
11736665_a_at
11740474_a_at
1190_at
1554199_PM_at
1554199_at
16748711
208121_PM_s_at
208121_s_at
32199_at
3406310
3406330
3406331
3406352
3406356
3406357
3406358
3406359
3406361
3406363
3406364
3406365
3406366
3406367
3406368
3406369
3406371
3406372
3406373
3406375
3406377
3406378
3406379
3406381
3406382
3406385
3406386
3406387
3406388
3406391
3406393
3406397
3406398
3406399
3406400
3406401
3406402
3406403
3406404
3406405
3406406
3406412
42420_at
5800
7954143
81908_at
A_14_P101167
A_14_P125795
A_23_P204304
A_24_P76809
GE560480
GE59000
GE899536
GO:0000902
GO:0002376
GO:0002548
GO:0003013
GO:0003014
GO:0003093
GO:0003105
GO:0003824
GO:0004721
GO:0004725
GO:0005001
GO:0005515
GO:0005576
GO:0005615
GO:0005886
GO:0006470
GO:0007155
GO:0007411
GO:0010812
GO:0010977
GO:0016020
GO:0016311
GO:0016324
GO:0016328
GO:0016787
GO:0016791
GO:0017147
GO:0023052
GO:0030027
GO:0030032
GO:0030154
GO:0030424
GO:0030426
GO:0032835
GO:0034330
GO:0035335
GO:0036060
GO:0036211
GO:0042803
GO:0043005
GO:0043197
GO:0043226
GO:0045296
GO:0048856
GO:0048870
GO:0050807
GO:0060089
GO:0070062
GO:0072112
GO:0090090
GO:0090260
GO:0098839
GO:0098978
GO:0098982
GO:0140096
HMNXSV003033779
Hs2.258609.7.S1_3p_at
ILMN_1720113
ILMN_2316878
PH_hs_0022752
TC12000203.hg
Z48541_at
g13677212_3p_s_at
Participates
as a candidate of
(PTPRO,PTPRS) [plasma membrane] (Homo sapiens)
Cross References
RefSeq
NP_109596.1
,
NP_109594.1
,
NP_002839.1
,
NP_109592.1
,
NP_109595.1
,
NP_109593.1
Guide to Pharmacology - Targets
1863
OpenTargets
ENSG00000151490
IntEnz
3.1.3.48
HPA
ENSG00000151490-PTPRO
GeneCards
Q16827
Ensembl
ENST00000543886
,
ENST00000674316
,
ENST00000542557
,
ENSP00000501352
,
ENSP00000437571
,
ENST00000348962
,
ENSP00000343434
,
ENSP00000281171
,
ENSP00000393449
,
ENSP00000439234
,
ENSP00000444173
,
ENST00000674388
,
ENST00000674261
,
ENST00000281171
,
ENSG00000151490
,
ENST00000544244
,
ENSP00000501494
,
ENST00000442921
,
ENST00000445537
,
ENSP00000501538
,
ENSP00000404188
PRO
Q16827
Pharos - Targets
Q16827
Orphanet
20296
HMDB Protein
HMDBP08948
PDB
2G59
,
2GJT
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P08581 MET
7
p-Y1234,Y1235,Y1356-MET [plasma membrane]
(R-HSA-6807014)
p-Y1349,Y1356-MET [plasma membrane]
(R-HSA-6807032)
MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(R-HSA-8875181)
MonoUb-K,p-Y1003,4Y-MET [plasma membrane]
(R-HSA-8875180)
p-Y1003,4Y-MET [plasma membrane]
(R-HSA-8874689)
MET [plasma membrane]
(R-HSA-419603)
p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(R-HSA-6806973)
0.59
2
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