GHSR is a receptor for ghrelin

Stable Identifier
R-HSA-947647
Type
Reaction
Species
Homo sapiens
Compartment
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Summation

Ghrelin is a 27 or 28 residue long peptide that is the ligand of Growth hormone secretagogue receptor type 1 (GHSR). O-octanoylation or O-decanoylation is essential for ghrelin activity. GHSR activation induces the release of growth hormone from the pituitary. It has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.

Literature References
PubMed ID Title Journal Year
10604470 Ghrelin is a growth-hormone-releasing acylated peptide from stomach

Kojima, M, Hosoda, H, Date, Y, Nakazato, M, Matsuo, H, Kangawa, K

Nature 1999
11322507 Growth hormone secretagogue receptor family members and ligands

Smith, RG, Leonard, R, Bailey, AR, Palyha, O, Feighner, S, Tan, C, McKee, KK, Pong, SS, Griffin, P, Howard, A

Endocrine 2001
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