Ghrelin is a 27 or 28 residue long peptide that is the ligand of Growth hormone secretagogue receptor type 1 (GHSR). O-octanoylation or O-decanoylation is essential for ghrelin activity. GHSR activation induces the release of growth hormone from the pituitary. It has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
Feighner, S, Leonard, R, Smith, RG, Howard, A, Pong, SS, Palyha, O, Bailey, AR, Tan, C, McKee, KK, Griffin, P
Date, Y, Kangawa, K, Hosoda, H, Matsuo, H, Kojima, M, Nakazato, M
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