GHSR is a receptor for ghrelin

Stable Identifier
R-HSA-947647
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, extracellular region
ReviewStatus
5/5
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GHSR is a receptor for ghrelin
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Ghrelin is a 27 or 28 residue long peptide that is the ligand of Growth hormone secretagogue receptor type 1 (GHSR). O-octanoylation or O-decanoylation is essential for ghrelin activity. GHSR activation induces the release of growth hormone from the pituitary. It has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
Literature References
PubMed ID Title Journal Year
11322507 Growth hormone secretagogue receptor family members and ligands

Feighner, S, Leonard, R, Smith, RG, Howard, A, Pong, SS, Palyha, O, Bailey, AR, Tan, C, McKee, KK, Griffin, P

Endocrine 2001
10604470 Ghrelin is a growth-hormone-releasing acylated peptide from stomach

Date, Y, Kangawa, K, Hosoda, H, Matsuo, H, Kojima, M, Nakazato, M

Nature 1999
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Ghsr is a receptor for ghrelin (Rattus norvegicus)
Authored
Jupe, S  (2010-06-18)
Reviewed
Jassal, B  (2010-06-09)
Created
Jupe, S  (2010-09-10)
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