Reactome | UBE2O [cytosol]

UBE2O [cytosol]

Stable Identifier

R-HSA-947641

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ubiquitin-conjugating enzyme E2 O, UBE2O_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9C0C9 UBE2O

Gene Names

UBE2O, KIAA1734

Chain

chain:1-1292

Reference Genes

BioGPS Gene:63893 UBE2O

COSMIC (genes):UBE2O UBE2O

CTD Gene:63893 UBE2O

dbSNP Gene:63893 UBE2O

ENSEMBL:ENSG00000175931 UBE2O

HGNC:29554 UBE2O

KEGG:hsa:63893 UBE2O

Monarch:63893 UBE2O

NCBI Gene:63893 UBE2O

OMIM:617649 UBE2O

UCSC:Q9C0C9 UBE2O

Reference Transcript

RefSeq:NM_022066.3 UBE2O

Other Identifiers

11743992_at

1554814_PM_at

1554814_at

16849217

218141_PM_at

218141_at

3771544

3771545

3771546

3771548

3771550

3771551

3771552

3771553

3771554

3771555

3771556

3771557

3771558

3771559

3771560

3771561

3771562

3771563

3771564

3771565

3771566

3771567

3771568

3771569

3771570

3771594

3771595

3771596

54633_at

63893

8018708

A_24_P128068

A_24_P172993

GE474034

GE55658

GO:0003723

GO:0003824

GO:0004842

GO:0005515

GO:0005524

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006513

GO:0016192

GO:0016567

GO:0016604

GO:0016740

GO:0030513

GO:0042147

GO:0043226

GO:0061630

GO:0061631

GO:0070534

GO:0140096

HMNXSV003009459

Hs2.16130.2.S1_3p_at

ILMN_1746579

PH_hs_0001487

TC17001898.hg

g11545776_3p_at

Participates

as a candidate of

E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)

Inferred To

UBE2O [cytosol] (Bos taurus)

UBE2O [cytosol] (Canis familiaris)

UBE2O [cytosol] (Gallus gallus)

UBE2O [cytosol] (Sus scrofa)

Ube2o [cytosol] (Mus musculus)

Ube2o [cytosol] (Rattus norvegicus)

Dmel\CG10254 [cytosol] (Drosophila melanogaster)

Cross References

RefSeq

NP_071349.3

ENSEMBL

ENSP00000323687, ENST00000319380

OpenTargets

ENSG00000175931

IntEnz

2.3.2.24

HPA

ENSG00000175931-UBE2O

PRO

Q9C0C9

Pharos - Targets

Q9C0C9

GlyGen

Q9C0C9

HMDB Protein

HMDBP09303

PDB

7UN3, 7UN6

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UKG1 APPL1	1	APPL1 [endosome membrane] (R-HSA-373630)	0.718	6
UniProt:P62987 UBA52	20	UBA52(1-76) [endocytic vesicle membrane] (R-HSA-939236) Ub-33-UBA52(1-76) [mitochondrial outer membrane] (R-HSA-6783187) Ub-63-UBA52(1-76) [mitochondrial outer membrane] (R-HSA-6783039) Ub-6-UBA52(1-76) [mitochondrial outer membrane] (R-HSA-6783072) Ub-11-UBA52(1-76) [mitochondrial outer membrane] (R-HSA-6783059) Ub-48-UBA52(1-76) [mitochondrial outer membrane] (R-HSA-6783049) Ub-29-UBA52(1-76) [mitochondrial outer membrane] (R-HSA-6783030) Ub-63-UBA52(1-76) [cytosol] (R-HSA-939169) UBA52(1-76) [lysosomal lumen] (R-HSA-9660000) UBA52(1-76) [cytosol] (R-HSA-939203) p-S65-UBA52(1-76) [mitochondrial outer membrane] (R-HSA-9834996) Ub-48-UBA52(1-76) [cytosol] (R-HSA-939250) UBA52(1-76) [mitochondrial outer membrane] (R-HSA-9834955) UBA52(1-76) [late endosome lumen] (R-HSA-9660003) Ub-6-UBA52(1-76) [nucleoplasm] (R-HSA-6782616) Ub-63-UBA52(1-76) [nucleoplasm] (R-HSA-6782530) Ub-48-UBA52(1-76) [nucleoplasm] (R-HSA-5683034) UBA52(1-76) [nucleoplasm] (R-HSA-939844) Ub-11-UBA52(1-76) [cytosol] (R-HSA-3095931) Ub-63-UBA52(1-76) [plasma membrane] (R-HSA-939851)	0.659	3
UniProt:O43709 WBSCR22	1	WBSCR22 [nucleoplasm] (R-HSA-6790981)	0.643	4
UniProt:Q92560 BAP1	1	BAP1 [nucleoplasm] (R-HSA-5689665)	0.643	4
UniProt:P31751 AKT2	7	p-T309,S474-AKT2 [nucleoplasm] (R-HSA-202087) p-T309,S474-AKT2 [cytosol] (R-HSA-202062) p-S474-AKT2 [plasma membrane] (R-HSA-2317312) AKT2 [plasma membrane] (R-HSA-202053) AKT2 [cytosol] (R-HSA-49859) p-T309-AKT2 [cytosol] (R-HSA-202066) p-T309,S474-AKT2 [plasma membrane] (R-HSA-202056)	0.623	4
UniProt:P67809 YBX1	5	p-S32,S36-YBX1 [nucleoplasm] (R-HSA-9733227) p-S32,S36-YBX1 [cytosol] (R-HSA-9736837) YBX1 [cytosol] (R-HSA-9736840) YBX1 [nucleoplasm] (R-HSA-72041) YBX1 [extracellular region] (R-HSA-9017791)	0.547	2
UniProt:Q9UGY1 NOL12	1	NOL12 [nucleoplasm] (R-HSA-6791195)	0.527	2
UniProt:P12644 BMP4	4	BMP4 [endoplasmic reticulum lumen] (R-HSA-8956775) p-BMP4 [endoplasmic reticulum lumen] (R-HSA-8956944) BMP4 [extracellular region] (R-HSA-8858573) BMP4(20-408) [extracellular region] (R-HSA-2396280)	0.527	2
UniProt:Q6NZI2 PTRF	2	PTRF [nucleoplasm] (R-HSA-74981) CAVIN1 [plasma membrane] (R-HSA-9714278)	0.527	3
UniProt:P04608 tat	1	Tat (P04608) [nucleoplasm] (R-HIV-175856)	0.462	2

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