Reactome | UBE2D4 [cytosol]

UBE2D4 [cytosol]

Stable Identifier

R-HSA-947623

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ubiquitin-conjugating enzyme E2 D4, UB2D4_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y2X8 UBE2D4

Gene Names

UBE2D4, UBCH5D

Chain

chain:1-147

Reference Genes

BioGPS Gene:51619 UBE2D4

COSMIC (genes):UBE2D4 UBE2D4

CTD Gene:51619 UBE2D4

dbSNP Gene:51619 UBE2D4

ENSEMBL:ENSG00000078967 UBE2D4

HGNC:21647 UBE2D4

KEGG Gene (Homo sapiens):51619 UBE2D4

Monarch:51619 UBE2D4

NCBI Gene:51619 UBE2D4

UCSC:Q9Y2X8 UBE2D4

Reference Transcript

RefSeq:NM_015983.3 UBE2D4

Other Identifiers

0005550458

11720114_a_at

17045566

218837_s_at

221949_at

2999641

2999644

2999646

2999648

2999651

2999653

2999661

2999662

2999663

2999665

2999667

2999669

2999671

4826759C_3p_s_at

4866907C_3p_s_at

51619

51774_s_at

57309_f_at

58900_at

62949_at

65521_at

8132523

A_23_P374767

A_33_P3637909

GE58637

GE80831

GO:0000151

GO:0000166

GO:0000209

GO:0003674

GO:0004842

GO:0005515

GO:0005524

GO:0005575

GO:0005622

GO:0005634

GO:0006464

GO:0006511

GO:0008150

GO:0009056

GO:0016567

GO:0016740

GO:0019899

GO:0031625

GO:0032991

GO:0035519

GO:0043167

GO:0043226

GO:0044314

GO:0061631

GO:0070534

GO:0070936

GO:0070979

GO:0085020

HMNXSV003026886

Hs.237946.0.A1_3p_at

ILMN_1707084

PH_hs_0001689

PH_hs_0038169

TC07000268.hg

g8393718_3p_s_at

Participates

as a candidate of

E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)

as a member of

UBE2D1/2/3/4 [cytosol] (Homo sapiens)

Inferred To

UBE2D1 [cytosol] (Dictyostelium discoideum)

ube2d4 [cytosol] (Danio rerio)

Homologues of UBE2D1 [cytosol] (Caenorhabditis elegans)

Homologues of UBE2D1 [cytosol] (Dictyostelium discoideum)

Homologues of UBE2D1 [cytosol] (Drosophila melanogaster)

Homologues of UBE2D1 [cytosol] (Saccharomyces cerevisiae)

Homologues of UBE2D1 [cytosol] (Schizosaccharomyces pombe)

ubc14 [cytosol] (Schizosaccharomyces pombe)

UBE2D4 [cytosol] (Bos taurus)

UBE2D4 [cytosol] (Sus scrofa)

UBE2D4 [cytosol] (Xenopus tropicalis)

ubc4 [cytosol] (Schizosaccharomyces pombe)

ubc-19 [cytosol] (Caenorhabditis elegans)

UBC5 [cytosol] (Saccharomyces cerevisiae)

Dmel\CG10862 [cytosol] (Drosophila melanogaster)

eff [cytosol] (Drosophila melanogaster)

ubc-24 [cytosol] (Caenorhabditis elegans)

UBC4 [cytosol] (Saccharomyces cerevisiae)

let-70 [cytosol] (Caenorhabditis elegans)

ubcB [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

NP_057067.1

OpenTargets

ENSG00000078967

GeneCards

Q9Y2X8

HPA

ENSG00000078967-UBE2D4

Ensembl

ENSG00000078967, ENST00000222402, ENSP00000222402

PRO

Q9Y2X8

Pharos - Targets

Q9Y2X8

HMDB Protein

HMDBP11571

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9P0P0 RNF181	1	RNF181 [cytoplasm] (R-HSA-8939317)	0.666	4
UniProt:P19388 POLR2E	2	POLR2E [cytosol] (R-HSA-1964438) POLR2E [nucleoplasm] (R-HSA-83713)	0.556	3
UniProt:Q9UHC7 MKRN1	2	MKRN1 [cytosol] (R-HSA-976042) p-S109-MKRN1 [cytosol] (R-HSA-8948758)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:Q9Y6K9 IKBKG	12	IKBKG D406V [cytosol] (R-HSA-5262943) IKBKG L153R [cytosol] (R-HSA-5262879) IKBKG [cytosol] (R-HSA-168108) K63polyUb-NEMO [cytosol] (R-HSA-202530) Ub-285-IKBKG [cytosol] (R-HSA-741397) IKBKG C417R [cytosol] (R-HSA-5262858) IKBKG R175P [cytosol] (R-HSA-5262916) IKBKG [nucleoplasm] (R-HSA-4755413) IKBKG 420Wro447 [cytosol] (R-HSA-5262978) IKBKG E391* [cytosol] (R-HSA-5262924) SUMO1-K277,K309-IKBKG [nucleoplasm] (R-HSA-4755449) IKBKG R173G [cytosol] (R-HSA-5262966)	0.556	3
UniProt:Q6ZNA4 RNF111	2	RNF111 [cytosol] (R-HSA-975981) RNF111 [nucleoplasm] (R-HSA-2186765)	0.553	2