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ERAP1 [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-947609
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
Endoplasmic reticulum aminopeptidase 1, ERAP1_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Homo sapiens)
Trimming of peptides in ER (Homo sapiens)
ERAP1/2 [endoplasmic reticulum lumen] (Homo sapiens)
ERAP1 [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NZ08 ERAP1
Gene Names
ERAP1, APPILS, ARTS1, KIAA0525, UNQ584/PRO1154
Chain
chain:1-941
Reference Genes
BioGPS Gene:51752 ERAP1
COSMIC (genes):ERAP1 ERAP1
CTD Gene:51752 ERAP1
dbSNP Gene:51752 ERAP1
ENSEMBL:ENSG00000164307 ERAP1
HGNC:18173 ERAP1
KEGG:hsa:51752 ERAP1
Monarch:51752 ERAP1
NCBI Gene:51752 ERAP1
OMIM:606832 ERAP1
UCSC:Q9NZ08 ERAP1
Reference Transcript
RefSeq:NM_001198541.1 ERAP1
RefSeq:XM_011543486.2 ERAP1
RefSeq:XM_017009582.1 ERAP1
RefSeq:NM_001040458.1 ERAP1
RefSeq:NM_016442.3 ERAP1
Other Identifiers
11724601_s_at
11724602_a_at
11727884_at
11727885_at
11749003_a_at
16998368
209788_PM_s_at
209788_s_at
210385_PM_s_at
210385_s_at
214012_3p_at
214012_PM_at
214012_at
214034_PM_at
214034_at
2868132
2868133
2868134
2868140
2868141
2868142
2868143
2868144
2868145
2868146
2868151
2868152
2868153
2868154
2868155
2868156
2868157
2868158
2868159
2868160
2868161
2868167
2868168
2868169
2868170
2868172
2868173
2868176
2868177
2868178
2868179
2868180
2868181
2868182
2868183
39265_at
51752
8113250
92012_at
A_23_P167452
A_24_P63537
A_33_P3413701
GE79649
GO:0001525
GO:0002250
GO:0002376
GO:0002474
GO:0003824
GO:0004175
GO:0004177
GO:0005138
GO:0005151
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005783
GO:0005788
GO:0005789
GO:0005829
GO:0006508
GO:0006509
GO:0008217
GO:0008233
GO:0008235
GO:0008237
GO:0008270
GO:0009617
GO:0016020
GO:0016787
GO:0019885
GO:0030154
GO:0042277
GO:0043171
GO:0043226
GO:0045088
GO:0045444
GO:0045766
GO:0046872
GO:0070006
GO:0070062
GO:0140096
HMNXSV003010332
HMNXSV003027650
HMNXSV003045348
Hs.247043.3.S1_3p_at
Hs.247043.3.S1_3p_s_at
Hs.247043.3.S1_3p_x_at
Hs.247043.3.S2_3p_at
ILMN_1752145
ILMN_2336220
PH_hs_0028431
TC05001617.hg
g6381988_3p_a_at
g6642986_3p_at
Participates
as a member of
ERAP1/2 [endoplasmic reticulum lumen] (Homo sapiens)
Inferred To
Dmel\CG6071 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
ERAP1 [endoplasmic reticulum lumen]
(Bos taurus)
ERAP1 [endoplasmic reticulum lumen]
(Caenorhabditis elegans)
ERAP1 [endoplasmic reticulum lumen]
(Canis familiaris)
ERAP1 [endoplasmic reticulum lumen]
(Dictyostelium discoideum)
ERAP1 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
ERAP1 [endoplasmic reticulum lumen]
(Gallus gallus)
ERAP1 [endoplasmic reticulum lumen]
(Mus musculus)
ERAP1 [endoplasmic reticulum lumen]
(Rattus norvegicus)
ERAP1 [endoplasmic reticulum lumen]
(Sus scrofa)
ERAP1 [endoplasmic reticulum lumen]
(Xenopus tropicalis)
Dmel\CG40470 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
Dmel\CG4467 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
Homologues of ERAP1 [endoplasmic reticulum lumen]
(Caenorhabditis elegans)
Homologues of ERAP1 [endoplasmic reticulum lumen]
(Dictyostelium discoideum)
Homologues of ERAP1 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
pepCG2111 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
Cross References
Guide to Pharmacology - Targets
1566
OpenTargets
ENSG00000164307
ENSEMBL
ENSP00000296754
,
ENST00000296754
,
ENSG00000164307
,
ENSP00000406304
,
ENST00000443439
ZINC - Substances
ERAP1_HUMAN
ZINC target
Q9NZ08
PRO
Q9NZ08
GlyGen
Q9NZ08
PDB
6T6R
,
6MGQ
,
3MDJ
,
3RJO
,
5J5E
,
7Z28
,
6RQX
,
7MWB
,
7MWC
,
6Q4R
,
3QNF
,
6RYF
,
6M8P
,
2YD0
HPA
ENSG00000164307-ERAP1
GeneCards
ERAP1
Pharos - Targets
Q9NZ08
ZINC - Predictions - Purchasable
ERAP1_HUMAN
Orphanet
ERAP1
HMDB Protein
HMDBP09219
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