Ub-63-UBB(1-76) [cytosol]

Stable Identifier
R-HSA-939224
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ub-63-UBB, K63 ubiquitin (UBB 1)
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P0CG47 UBB
Gene Names
UBB
Chain
chain:1-76, chain:77-152, chain:153-228, propeptide:-
Reference Genes
BioGPS Gene:7314 UBB
COSMIC (genes):UBB UBB
CTD Gene:7314 UBB
dbSNP Gene:7314 UBB
ENSEMBL:ENSG00000170315 UBB
HGNC:12463 UBB
KEGG Gene (Homo sapiens):7314 UBB
Monarch:7314 UBB
NCBI Gene:7314 UBB
OMIM:191339 UBB
Reference Transcript
Other Identifiers
0006660142
11732126_x_at
11744327_x_at
13048
1323_at
16831434
200633_at
2578171
2578172
2578173
2578174
2KHW
2MBB
2MRO
2MSG
2N13
32153_s_at
3712045
3712046
3712047
3712048
3712050
3712051
3712052
3712053
3712054
3712055
3712056
3714880
3714882
3714883
3714884
3714885
3714889
41344
49132
4UEL
4UF6
4WHV
4WLR
4WUR
4XOF
4ZFR
4ZFT
4ZPZ
4ZUX
5BNB
5CAW
5CRA
5CVM
5CVN
5CVO
5D0K
5D0M
5DFL
5DK8
5E6J
5EDV
5EMZ
5EYA
5GJQ
5H7S
5IBK
5IFR
5JBY
5JG6
5JP3
5JTJ
5JTV
5K9P
5KGF
5KHY
5KYC
5KYD
5KYE
5KYF
5L8H
5L8W
5L9T
5LN1
5LRV
5LRW
5LRX
5M93
5MNJ
5N2W
5N38
5NL5
5NLJ
5NVG
5O44
5O6T
5OHK
5OHL
5OHN
5OHP
5TOF
5TOG
5TUT
5TXK
5UJL
5UJN
5ULF
5ULH
5ULK
5V1Y
5V1Z
5VEY
5VF0
5VNZ
5VO0
5VZM
5VZW
5W46
5WFI
5X3M
5X3N
5X3O
5XBO
5XDP
5XK4
5XK5
5XPK
5YDR
5YIJ
5YIK
5YMY
5YT6
5ZBU
6ASR
6BVA
6BYH
6C16
6CP2
6DGF
6EI1
6FDK
6FGE
6FTX
6FX4
6FYH
6GLC
6GZS
6H4H
6HEI
6HEK
6IF1
6ISU
6JB6
6JB7
6MSB
6MSD
6MSE
6MSG
6N13
6NJG
7314
8005166
A_14_P126655
A_23_P27215
A_24_P113109
AAH00379
AAH09301
AAH15127
AAH26301
AAH31027
AAH38999
AAH46123
AAV38907
AB089617
AC093484
ACV87175
B4DV12
BAC56955
BC000379
BC009301
BC015127
BC026301
BC031027
BC038999
BC046123
BT020104
CAA28495
CAB013048
CCDS11177
CH471222
EAX04501
EAX04502
ENSG00000170315
ENSP00000304697
ENSP00000379178
ENSP00000379180
ENSP00000478771
ENST00000302182
ENST00000302182.7
ENST00000395837
ENST00000395837.1
ENST00000395839
ENST00000395839.5
ENST00000614404
ENST00000614404.1
EntrezGene:7314
EntrezGene:UBB
g11024713_3p_at
GE79998
GO:0000003
GO:0000122
GO:0000187
GO:0000209
GO:0000715
GO:0000717
GO:0000902
GO:0002376
GO:0002755
GO:0002756
GO:0003674
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005741
GO:0005768
GO:0005783
GO:0005789
GO:0005829
GO:0005886
GO:0006259
GO:0006283
GO:0006294
GO:0006296
GO:0006297
GO:0006464
GO:0006605
GO:0006625
GO:0006810
GO:0006950
GO:0007049
GO:0007141
GO:0007144
GO:0007165
GO:0007179
GO:0007249
GO:0007254
GO:0007267
GO:0008150
GO:0008219
GO:0008584
GO:0008585
GO:0009056
GO:0009058
GO:0010008
GO:0015031
GO:0016055
GO:0016192
GO:0016197
GO:0016567
GO:0016579
GO:0019058
GO:0019068
GO:0019221
GO:0019899
GO:0019941
GO:0019985
GO:0021888
GO:0022607
GO:0030154
GO:0030512
GO:0030666
GO:0030705
GO:0031145
GO:0031386
GO:0031398
GO:0031410
GO:0031625
GO:0031982
GO:0033683
GO:0034641
GO:0034655
GO:0035666
GO:0036297
GO:0042276
GO:0042592
GO:0042769
GO:0043005
GO:0043025
GO:0043065
GO:0043066
GO:0043226
GO:0043488
GO:0043657
GO:0044267
GO:0044403
GO:0045944
GO:0047497
GO:0048812
GO:0048856
GO:0051092
GO:0051276
GO:0051403
GO:0051881
GO:0055085
GO:0060612
GO:0060613
GO:0061024
GO:0061136
GO:0061418
GO:0065003
GO:0070062
GO:0070423
GO:0070498
GO:0070911
GO:0070987
GO:0072520
GO:0075733
GO:0097009
GO:1901214
GO:1902255
GO:1902527
GQ472200
HGNC:12463
HPA041344
HPA049132
ILMN_1762436
ILMN_2191428
IPR000626
IPR019954
IPR019956
IPR029071
J3QKN0
J3QS39
J3QSA3
MIM:191339
NM_001281716
NM_001281717
NM_001281718
NM_001281719
NM_001281720
NM_018955
NP_001268645
NP_001268646
NP_001268647
NP_001268648
NP_001268649
NP_061828
PF00240
PH_hs_0017263
PR00348
Q5U5U6
SM00213
TC17000187.hg
U49869_rna1_at
UBB
UBB-201
UBB-202
UBB-203
UBB-209
UPI0000002146
X04803
Participant Of
hasMember
Other forms of this molecule
UBB(77-152) [endocytic vesicle membrane]
UBB(1-76) [endocytic vesicle membrane]
UBB(153-228) [endocytic vesicle membrane]
Ub-33-UBB(1-76) [mitochondrial outer membrane]
Ub-110-UBB(77-152) [mitochondrial outer membrane]
Ub-186-UBB(153-228) [mitochondrial outer membrane]
Ub-215-UBB(153-228) [mitochondrial outer membrane]
Ub-63-UBB(1-76) [mitochondrial outer membrane]
Ub-139-UBB(77-152) [mitochondrial outer membrane]
Ub-158-UBB(153-228) [mitochondrial outer membrane]
Ub-6-UBB(1-76) [mitochondrial outer membrane]
Ub-82-UBB(77-152) [mitochondrial outer membrane]
Ub-163-UBB(153-228) [mitochondrial outer membrane]
Ub-87-UBB(77-152) [mitochondrial outer membrane]
Ub-11-UBB(1-76) [mitochondrial outer membrane]
Ub-124-UBB(77-152) [mitochondrial outer membrane]
Ub-200-UBB(153-228) [mitochondrial outer membrane]
Ub-48-UBB(1-76) [mitochondrial outer membrane]
Ub-182-UBB(153-228) [mitochondrial outer membrane]
Ub-29-UBB(1-76) [mitochondrial outer membrane]
Ub-106-UBB(77-152) [mitochondrial outer membrane]
Ub-27-UBB(1-76) [mitochondrial outer membrane]
Ub-180-UBB(153-228) [mitochondrial outer membrane]
Ub-104-UBB(77-152) [mitochondrial outer membrane]
N6-glycyl-L-lysine-UBB(1-76) [cytosol]
N6-glycyl-L-lysine-UBB(153-228) [cytosol]
N6-glycyl-L-lysine-UBB(77-152) [cytosol]
Ub-106-UBB(77-152) [cytosol]
Ub-182-UBB(153-228) [cytosol]
Ub-29-UBB(1-76) [cytosol]
Ub-158-UBB(153-228) [cytosol]
Ub-82-UBB(77-152) [cytosol]
Ub-6-UBB(1-76) [cytosol]
Ub-33-UBB(1-76) [cytosol]
Ub-186-UBB(153-228) [cytosol]
Ub-110-UBB(77-152) [cytosol]
adenylatedG152-UBB(77-152) [nucleoplasm]
adenylatedG228-UBB(153-228) [nucleoplasm]
adenylatedG76-UBB(1-76) [nucleoplasm]
UBB [cytosol]
adenylatedG76-UBB(1-76) [cytosol]
adenylatedG228-UBB(153-228) [cytosol]
adenylatedG152-UBB(77-152) [cytosol]
Ub-124-UBB(77-152) [endoplasmic reticulum membrane]
Ub-48-UBB(1-76) [endoplasmic reticulum membrane]
Ub-200-UBB(153-228) [endoplasmic reticulum membrane]
UBB(153-228) [endoplasmic reticulum membrane]
UBB(77-152) [endoplasmic reticulum membrane]
UBB(1-76) [endoplasmic reticulum membrane]
UBB(153-228) [plasma membrane]
UBB(1-76) [plasma membrane]
UBB(77-152) [plasma membrane]
UBB(77-152) [endosome membrane]
UBB(1-76) [endosome membrane]
UBB(153-228) [endosome membrane]
Ub-27-UBB(1-76) [cytosol]
Ub-104-UBB(77-152) [cytosol]
Ub-180-UBB(153-228) [cytosol]
Ub-11-UBB(1-76) [cytosol]
Ub-163-UBB(153-228) [cytosol]
Ub-87-UBB(77-152) [cytosol]
Ub-139-UBB(77-152) [endosome membrane]
Ub-215-UBB(153-228) [endosome membrane]
Ub-63-UBB(1-76) [endosome membrane]
Ub-139-UBB(77-152) [plasma membrane]
Ub-63-UBB(1-76) [plasma membrane]
Ub-215-UBB(153-228) [plasma membrane]
Ub-27-UBB(1-76) [nucleoplasm]
Ub-180-UBB(153-228) [nucleoplasm]
Ub-104-UBB(77-152) [nucleoplasm]
Ub-106-UBB(77-152) [nucleoplasm]
Ub-182-UBB(153-228) [nucleoplasm]
Ub-29-UBB(1-76) [nucleoplasm]
Ub-139-UBB(77-152) [nucleoplasm]
Ub-63-UBB(1-76) [nucleoplasm]
Ub-215-UBB(153-228) [nucleoplasm]
Ub-124-UBB(77-152) [nucleoplasm]
Ub-48-UBB(1-76) [nucleoplasm]
Ub-200-UBB(153-228) [nucleoplasm]
Ub-11-UBB(1-76) [nucleoplasm]
Ub-87-UBB(77-152) [nucleoplasm]
Ub-163-UBB(153-228) [nucleoplasm]
Ub-186-UBB(153-228) [nucleoplasm]
Ub-110-UBB(77-152) [nucleoplasm]
Ub-33-UBB(1-76) [nucleoplasm]
Ub-82-UBB(77-152) [nucleoplasm]
Ub-6-UBB(1-76) [nucleoplasm]
Ub-158-UBB(153-228) [nucleoplasm]
UBB(77-152) [nucleoplasm]
UBB(1-76) [nucleoplasm]
UBB(153-228) [nucleoplasm]
Ub-48-UBB(1-76) [nucleoplasm]
Ub-124-UBB(77-152) [nucleoplasm]
Ub-200-UBB(153-228) [nucleoplasm]
Ub-139-UBB(77-152) [nucleoplasm]
Ub-215-UBB(153-228) [nucleoplasm]
Ub-63-UBB(1-76) [nucleoplasm]
UBB(153-228) [late endosome lumen]
UBB(77-152) [late endosome lumen]
UBB(1-76) [late endosome lumen]
Ub-48-UBB(1-76) [cytosol]
Ub-124-UBB(77-152) [cytosol]
Ub-200-UBB(153-228) [cytosol]
UBB(153-228) [cytosol]
UBB(77-152) [cytosol]
UBB(1-76) [cytosol]
UBB(77-152) [lysosomal lumen]
UBB(1-76) [lysosomal lumen]
UBB(153-228) [lysosomal lumen]
Ub-215-UBB(153-228) [cytosol]
Ub-139-UBB(77-152) [cytosol]
Inferred To
Ub-63-UBB(1-76) [cytosol] (Canis familiaris)
Ub-63-UBB(1-76) [cytosol] (Danio rerio)
Ub-63-UBB(1-76) [cytosol] (Dictyostelium discoideum)
Ub-63-UBB(1-76) [cytosol] (Drosophila melanogaster)
Ub-63-UBB(1-76) [cytosol] (Mus musculus)
Ub-63-UBB(1-76) [cytosol] (Plasmodium falciparum)
Ub-63-UBB(1-76) [cytosol] (Xenopus tropicalis)
Homologues of Ub-63-UBB(1-76) [cytosol] (Dictyostelium discoideum)
Modified Residues
Name
ubiquitinylated lysine at 63
Coordinate
63
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Orphanet
PDB
5KHY, 5JTJ, 5E6J, 4ZUX, 6DGF, 6FGE, 5ZD0, 5K9P, 5KYE, 6NJG, 5L8H, 6BVA, 6O96, 5GJQ, 6MSB, 5TOG, 5LRW, 5XK5, 5M93, 5ULK, 2N13, 5NVG, 5CAW, 5GO8, 4WLR, 5ULH, 5XBO, 5CVN, 5TXK, 2MRO, 5WFI, 6GZS, 6MSG, 5X3M, 5YT6, 5GOC, 6CP2, 5GOD, 5JG6, 5O44, 4ZFR, 4WUR, 5CVO, 6MSE, 5EYA, 6JB7, 4XOF, 5L9T, 5EDV, 5N2W, 5X3N, 5YDR, 5VO0, 5MNJ, 5OHK, 5BNB, 5VNZ, 5N38, 5KYF, 5GOI, 5VZM, 5LRX, 5UJL, 6H4H, 5L8W, 5IBK, 5XPK, 5OHP, 6IF1, 5LN1, 6C16, 6EI1, 6N13, 5VZW, 5YIK, 5XDP, 5GOJ, 5TUT, 5IFR, 6HEI, 2KHW, 6GLC, 5D0M, 5YMY, 5KYC, 5NLJ, 6HEK, 5ZBU, 6BYH, 5JTV, 5TOF, 5KYD, 4ZFT, 6FX4, 5ULF, 5CRA, 5GO7, 6JMA, 5DFL, 6JB6, 6ASR, 6JLT, 5XK4, 5O6T, 2MBB, 6FDK, 6ISU, 4WHV, 4UEL, 5GOB, 5KGF, 5CVM, 5DK8, 5V1Y, 6QF8, 5VEY, 6FTX, 5VF0, 6FYH, 5V1Z, 6MSD, 5X3O, 2MSG, 5GOG, 4UF6, 5JBY, 4ZPZ, 5UJN, 6QK9, 5OHL, 5LRV, 5NL5, 5H7S, 5GOH, 5OHN, 5EMZ, 5W46, 5D0K, 5JP3, 5GOK, 5YIJ
Interactors (24)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q15038 DAZP2      0.712 6
 UniProt:Q9Y3C5 RNF11      0.647 3
 UniProt:Q9UJ41 RABGEF1  2 0.632 6
 UniProt:Q9HAU4 SMURF2  2 0.623 4
 UniProt:P54727 RAD23B  2 0.621 4
 UniProt:Q9BSL1 UBAC1  1 0.621 3
 UniProt:Q60592 MAST2      0.589 2
 UniProt:Q9UJY5 GGA1  2 0.581 3
 UniProt:Q13077 TRAF1  3 0.564 2
 UniProt:P28562 DUSP1  1 0.544 2
 UniProt:Q96CS3 FAF2  2 0.527 3
 UniProt:Q9DLK6 Q9DLK6      0.524 2
 UniProt:P24610  1 0.524 2
 UniProt:Q9NZ52 GGA3  3 0.508 2
 UniProt:Q8IVM0 CCD50      0.508 2
 UniProt:Q9NRQ2 PLS4      0.488 2
 UniProt:Q9UHD9 UBQLN2  1 0.488 2
 UniProt:Q9H305 CDIP1      0.488 2
 UniProt:Q8N3F0 MTURN      0.488 2
 UniProt:Q96CS7 PKHB2      0.488 2
 UniProt:Q86VP1 TAX1BP1  1 0.488 2
 UniProt:Q6ICB0 DESI1      0.488 2
 UniProt:O00560 SDCBP  3 0.488 2
 UniProt:P03372 ESR1  8 0.462 2