IRAK4 is activated by autophosphorylation at 3 positions within the kinase activation loop, Thr-342, Thr-345 and Ser-346.
Cheng, H, Addona, T, Keshishian, H, Dahlstrand, E, Lu, C, Dorsch, M, Li, Z, Wang, A, Ocain, TD, Li, P, Parsons, TF, Jaffee, B, Xu, Y
Kawagoe, T, Sato, S, Jung, A, Yamamoto, M, Matsui, K, Kato, H, Uematsu, S, Takeuchi, O, Akira, S
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