Reactome | ATP1A3 [plasma membrane]

ATP1A3 [plasma membrane]

Stable Identifier

R-HSA-936803

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Sodium/potassium-transporting ATPase subunit alpha-3, AT1A3_HUMAN

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - Potential therapeutics for SARS (Homo sapiens)
        
        ATP1A:ATP1B:FXYD binds cardiac glycosides (Homo sapiens)
        
        ATP1A:ATP1B:FXYD [plasma membrane] (Homo sapiens)
        
        ATP1A [plasma membrane] (Homo sapiens)
        
        ATP1A3 [plasma membrane] (Homo sapiens)
        
        ATP1A:ATP1B:FXYD:cardiac glycosides [plasma membrane] (Homo sapiens)
        
        ATP1A:ATP1B:FXYD [plasma membrane] (Homo sapiens)
        
        ATP1A [plasma membrane] (Homo sapiens)
        
        ATP1A3 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P13637 ATP1A3

Gene Names

ATP1A3

Chain

chain:1-1013

Reference Genes

BioGPS Gene:478 ATP1A3

COSMIC (genes):ATP1A3 ATP1A3

CTD Gene:478 ATP1A3

dbSNP Gene:478 ATP1A3

ENSEMBL:ENSG00000105409 ATP1A3

HGNC:801 ATP1A3

KEGG:hsa:478 ATP1A3

Monarch:478 ATP1A3

NCBI Gene:478 ATP1A3

OMIM:182350 ATP1A3

UCSC:P13637 ATP1A3

Reference Transcript

Other Identifiers

11729577_a_at

11729578_x_at

11745200_a_at

16872648

214432_3p_at

214432_PM_at

214432_at

35670_at

3863341

3863343

3863344

3863345

3863346

3863347

3863349

3863350

3863352

3863354

3863355

3863357

3863358

3863359

3863361

3863362

3863364

3863365

3863366

3863367

3863369

3863370

3863371

3863372

3863373

3863374

3863375

3863376

3863377

3863378

3863379

478

8037079

A_23_P27472

A_33_P3283669

GE57903

GE84000

GO:0000166

GO:0001540

GO:0001917

GO:0003824

GO:0005215

GO:0005391

GO:0005515

GO:0005524

GO:0005783

GO:0005794

GO:0005886

GO:0005890

GO:0006813

GO:0006814

GO:0006883

GO:0008289

GO:0008556

GO:0010248

GO:0016020

GO:0016787

GO:0016887

GO:0030007

GO:0030424

GO:0031090

GO:0032809

GO:0034220

GO:0036376

GO:0043025

GO:0043226

GO:0045202

GO:0046872

GO:0051087

GO:0055085

GO:0060075

GO:0060342

GO:0071383

GO:0071805

GO:0086064

GO:0098984

GO:0140657

GO:1902600

GO:1903416

GO:1903561

GO:1904646

GO:1990239

GO:1990535

GO:1990573

HMNXSV003030689

Hs.274371.0.S1_3p_at

Hs.274371.0.S1_3p_x_at

ILMN_1689098

M37457_s_at

PH_hs_0033015

TC19001563.hg

Participates

as a member of

ATP1A [plasma membrane] (Homo sapiens)

Inferred To

atp1a3 [plasma membrane] (Xenopus tropicalis)

ATP1A3 [plasma membrane] (Bos taurus)

ATP1A3 [plasma membrane] (Canis familiaris)

ATP1A3 [plasma membrane] (Mus musculus)

ATP1A3 [plasma membrane] (Rattus norvegicus)

ATP1A3 [plasma membrane] (Sus scrofa)

atp1a3a [plasma membrane] (Danio rerio)

Cross References

Guide to Pharmacology - Targets

835

ENSEMBL

ENST00000648268, ENSP00000498113, ENST00000543770, ENST00000545399, ENSP00000437577, ENSP00000444688

OpenTargets

ENSG00000105409

HPA

ENSG00000105409-ATP1A3

PRO

P13637

Pharos - Targets

P13637

GlyGen

P13637

Orphanet

ATP1A3

HMDB Protein

HMDBP01416

PDB

8D3U, 8D3V, 8D3Y, 8D3W, 8D3X

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6NXG1 ESRP1	3	ESRP1(1-606)-RAF1(227-648) fusion [cytosol] (R-HSA-6802312) ESRP1(1-606)-p-RAF1(227-648) fusion [cytosol] (R-HSA-6802523) ESRP1 [nucleoplasm] (R-HSA-6803472)	0.556	3
UniProt:Q12888 TP53BP1	3	TP53BP1 [nucleoplasm] (R-HSA-61175) p-S25,S1778-TP53BP1 [nucleoplasm] (R-HSA-5683418) monoSUMO1-K-TP53BP1 [nucleoplasm] (R-HSA-2997591)	0.556	3
UniProt:P21453 S1PR1	1	S1PR1 [plasma membrane] (R-HSA-419340)	0.527	4