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RGS19 [plasma membrane]
Stable Identifier
R-HSA-921129
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Regulator of G-protein signaling 19, RGS19_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Active G alpha (i)–i1/i2/i3 binds RGS proteins (Homo sapiens)
G alpha (i):GTP:RGS [plasma membrane] (Homo sapiens)
RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane] (Homo sapiens)
RGS19 [plasma membrane] (Homo sapiens)
RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane] (Homo sapiens)
RGS19 [plasma membrane] (Homo sapiens)
G alpha (i) auto-inactivates by hydrolysing GTP to GDP (Homo sapiens)
RGS proteins active for G alpha (i) [plasma membrane] (Homo sapiens)
RGS19 [plasma membrane] (Homo sapiens)
G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Homo sapiens)
G alpha (i):GDP:RGS [plasma membrane] (Homo sapiens)
RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane] (Homo sapiens)
RGS19 [plasma membrane] (Homo sapiens)
RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane] (Homo sapiens)
RGS19 [plasma membrane] (Homo sapiens)
G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Homo sapiens)
G alpha (i):GDP:RGS [plasma membrane] (Homo sapiens)
RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane] (Homo sapiens)
RGS19 [plasma membrane] (Homo sapiens)
G alpha (i):GTP:RGS [plasma membrane] (Homo sapiens)
RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane] (Homo sapiens)
RGS19 [plasma membrane] (Homo sapiens)
RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane] (Homo sapiens)
RGS19 [plasma membrane] (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Active G alpha (q) binds RGS proteins (Homo sapiens)
G alpha (q):GTP:RGS [plasma membrane] (Homo sapiens)
RGS1,2,3,4,5,13,16,17,18,19,21 [plasma membrane] (Homo sapiens)
RGS19 [plasma membrane] (Homo sapiens)
RGS1,2,3,4,5,13,16,17,18,19,21 [plasma membrane] (Homo sapiens)
RGS19 [plasma membrane] (Homo sapiens)
G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Homo sapiens)
RGS proteins active for G alpha (q) [plasma membrane] (Homo sapiens)
RGS19 [plasma membrane] (Homo sapiens)
G alpha (q) in G (q):RGS complex is inactivated (Homo sapiens)
G alpha (q):GDP:RGS [plasma membrane] (Homo sapiens)
RGS1,2,3,4,5,13,16,17,18,19,21 [plasma membrane] (Homo sapiens)
RGS19 [plasma membrane] (Homo sapiens)
G alpha (q):GTP:RGS [plasma membrane] (Homo sapiens)
RGS1,2,3,4,5,13,16,17,18,19,21 [plasma membrane] (Homo sapiens)
RGS19 [plasma membrane] (Homo sapiens)
G alpha (q):RGS dissociates to inactive G alpha (q) (Homo sapiens)
G alpha (q):GDP:RGS [plasma membrane] (Homo sapiens)
RGS1,2,3,4,5,13,16,17,18,19,21 [plasma membrane] (Homo sapiens)
RGS19 [plasma membrane] (Homo sapiens)
RGS1,2,3,4,5,13,16,17,18,19,21 [plasma membrane] (Homo sapiens)
RGS19 [plasma membrane] (Homo sapiens)
G alpha (z) signalling events (Homo sapiens)
G alpha (z) auto-inactivates by hydrolysing GTP to GDP (Homo sapiens)
RGS proteins active for G alpha (z) [plasma membrane] (Homo sapiens)
RGS19 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P49795 RGS19
Gene Names
RGS19, GAIP, GNAI3IP
Chain
chain:1-217
Reference Genes
BioGPS Gene:10287 RGS19
COSMIC (genes):RGS19 RGS19
CTD Gene:10287 RGS19
dbSNP Gene:10287 RGS19
ENSEMBL:ENSG00000171700 RGS19
HGNC:13735 RGS19
KEGG Gene (Homo sapiens):10287 RGS19
Monarch:10287 RGS19
NCBI Gene:10287 RGS19
OMIM:605071 RGS19
UCSC:P49795 RGS19
Reference Transcript
RefSeq:NM_005873.2 RGS19
RefSeq:XM_011528486.2 RGS19
RefSeq:XM_011528485.2 RGS19
RefSeq:NM_001039467.1 RGS19
Other Identifiers
10287
11718915_a_at
16921433
204336_s_at
34268_at
3914308
3914309
3914310
3914311
3914312
3914313
3914314
3914316
3914317
3914319
3914320
3914321
3914322
3914323
3914324
3914325
3914326
8067802
A_23_P257014
A_33_P3211956
GE60145
GO:0001965
GO:0003674
GO:0003924
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005794
GO:0005886
GO:0005903
GO:0006914
GO:0007165
GO:0007186
GO:0007264
GO:0008150
GO:0009056
GO:0009968
GO:0016020
GO:0030136
GO:0031410
GO:0043226
GO:0045121
GO:0045471
ILMN_1677085
PH_hs_0019765
TC20001046.hg
TC20001720.hg
X91809_at
g5031704_3p_a_at
Participant Of
hasMember
RGS proteins active for G alpha (i) [plasma membrane]
RGS proteins active for G alpha (q) [plasma membrane]
RGS1,2,3,4,5,13,16,17,18,19,21 [plasma membrane]
RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane]
hasCandidate
RGS proteins active for G alpha (z) [plasma membrane]
Inferred To
rgs-1 [plasma membrane] (Caenorhabditis elegans)
rgs-4 [plasma membrane] (Caenorhabditis elegans)
SST2 [plasma membrane] (Saccharomyces cerevisiae)
RGS19 [plasma membrane] (Canis familiaris)
RGS19 [plasma membrane] (Dictyostelium discoideum)
RGS19 [plasma membrane] (Gallus gallus)
RGS19 [plasma membrane] (Sus scrofa)
RGS19 [plasma membrane] (Xenopus tropicalis)
rgs-2 [plasma membrane] (Caenorhabditis elegans)
Dhit [plasma membrane] (Drosophila melanogaster)
rgs1 [plasma membrane] (Schizosaccharomyces pombe)
Rgs19 [plasma membrane] (Mus musculus)
Rgs19 [plasma membrane] (Rattus norvegicus)
Homologues of RGS19 [plasma membrane] (Caenorhabditis elegans)
Homologues of RGS19 [plasma membrane] (Dictyostelium discoideum)
rgs19 [plasma membrane] (Danio rerio)
Cross References
RefSeq
XP_011526788.1
,
NP_001034556.1
,
NP_005864.1
,
XP_011526787.1
OpenTargets
ENSG00000171700
GeneCards
P49795
HPA
ENSG00000171700-RGS19
Ensembl
ENST00000332298
,
ENSG00000171700
,
ENSP00000333194
,
ENSP00000378483
,
ENST00000395042
PRO
P49795
PDB
1CMZ
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P49639 HOXA1
1
HOXA1 [nucleoplasm]
(R-HSA-5617464)
0.556
3
UniProt:Q12837 POU4F2
1
POU4F2 [nucleoplasm]
(R-HSA-6804414)
0.556
3
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