Transferrin endocytosis and recycling

Stable Identifier
R-HSA-917977
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Transferrin endocytosis and recycling
Click the image above or here to open this pathway in the Pathway Browser

Endocytosis of iron loaded transferrin/receptor complex leads, after acidification of the endosome, to the separation of iron and its diffusion out of the vesicle. The endosome is not fused with a lysosome but recycles its content back to the cell surface where soon transferrin dissociates from its receptor (Dautry-Varsat, 1986).

Literature References
PubMed ID Title Journal Year
2874839 Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor

Dautry-Varsat, A

Biochimie 1986
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
transferrin transport (0033572)
Orthologous Events
Transferrin endocytosis and recycling (Bos taurus)
Transferrin endocytosis and recycling (Caenorhabditis elegans)
Transferrin endocytosis and recycling (Canis familiaris)
Transferrin endocytosis and recycling (Danio rerio)
Transferrin endocytosis and recycling (Dictyostelium discoideum)
Transferrin endocytosis and recycling (Drosophila melanogaster)
Transferrin endocytosis and recycling (Gallus gallus)
Transferrin endocytosis and recycling (Mus musculus)
Transferrin endocytosis and recycling (Plasmodium falciparum)
Transferrin endocytosis and recycling (Rattus norvegicus)
Transferrin endocytosis and recycling (Saccharomyces cerevisiae)
Transferrin endocytosis and recycling (Schizosaccharomyces pombe)
Transferrin endocytosis and recycling (Sus scrofa)
Transferrin endocytosis and recycling (Xenopus tropicalis)
Cross References
BioModels Database
Authored
Stephan, R  (2010-07-11)
Reviewed
D'Eustachio, P  (2010-11-05)
Created
Jassal, B  (2010-07-30)
Cite Us!