The iron ions that are no longer bound to transferrin are reduced by the metalloreductase STEAP3, an endosomal membrane protein. The electron donor partner of the enzyme is unknown (Ohgami et al, 2005; Ohgami et al, 2006).
Fleming, MD, Ohgami, RS, Fujiwara, Y, Chen, J, Antiochos, B, Greer, EL, Campagna, DR, Barker, JE, McDonald, A, Sharp, JJ
Fleming, MD, Ohgami, RS, Campagna, DR, McDonald, A
oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor of STEAP3-like proteins [endosome membrane]
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