GABA loaded synaptic vesicle Docking and Priming

Stable Identifier
R-HSA-917744
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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GABA loaded synaptic vesicles are docked at the presynaptic terminal membrane by a number of proteins including Rab3a, RIM (Rab3a interaction protein) and Munc 13. The docked GABA vesicles are primed by the SNARE complex that includes synaptobrevin, SNAP 25 and syntaxin1.

Literature References
PubMed ID Title Journal Year
16722236 The role of SNARE proteins in trafficking and function of neurotransmitter transporters

Quick, MW

Handb Exp Pharmacol 2006
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
SNARE binding activity of GABA Loaded synaptic vesicle [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created