Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
CHMP5 [cytosol]
Stable Identifier
R-HSA-917694
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Charged multivesicular body protein 5, CHMP5_HUMAN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Budding and maturation of HIV virion (Homo sapiens)
HIV Virion Budding (Homo sapiens)
Virion Budding Complex [plasma membrane] (Homo sapiens)
Vps/Vta1 [cytosol] (Homo sapiens)
CHMP5 [cytosol] (Homo sapiens)
Recruitment Of HIV Virion Budding Machinery (Homo sapiens)
Virion Budding Complex [plasma membrane] (Homo sapiens)
Vps/Vta1 [cytosol] (Homo sapiens)
CHMP5 [cytosol] (Homo sapiens)
Vps/Vta1 [cytosol] (Homo sapiens)
CHMP5 [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Endosomal Sorting Complex Required For Transport (ESCRT) (Homo sapiens)
ESCRT Disassembly (Homo sapiens)
Vps/Vta1 [cytosol] (Homo sapiens)
CHMP5 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NZZ3 CHMP5
Gene Names
CHMP5, C9orf83, SNF7DC2, CGI-34, HSPC177, PNAS-114, PNAS-2
Chain
chain:1-219
Reference Genes
BioGPS Gene:51510 CHMP5
COSMIC (genes):CHMP5 CHMP5
CTD Gene:51510 CHMP5
dbSNP Gene:51510 CHMP5
ENSEMBL:ENSG00000086065 CHMP5
HGNC:26942 CHMP5
Monarch:51510 CHMP5
NCBI Gene:51510 CHMP5
OMIM:610900 CHMP5
UCSC:Q9NZZ3 CHMP5
Reference Transcript
RefSeq:NM_016410.5 CHMP5
RefSeq:NM_001195536.1 CHMP5
Other Identifiers
11718655_s_at
11760624_at
17084268
218085_PM_at
218085_at
219356_3p_s_at
219356_PM_s_at
219356_s_at
3166845
3166846
3166848
3166851
3166855
3166856
3166858
3166860
3166863
3166864
3166867
3166868
3166869
3166870
4006881
4006884
44853_s_at
51510
64109_at
80189_at
8154785
A_23_P83278
GE501730
GE58629
GO:0000421
GO:0000776
GO:0000815
GO:0001778
GO:0001919
GO:0005515
GO:0005634
GO:0005643
GO:0005737
GO:0005765
GO:0005768
GO:0005771
GO:0005828
GO:0005829
GO:0005886
GO:0006900
GO:0006914
GO:0006997
GO:0007034
GO:0007040
GO:0007080
GO:0008333
GO:0010008
GO:0010824
GO:0015031
GO:0016020
GO:0016192
GO:0030154
GO:0030218
GO:0030496
GO:0031410
GO:0031468
GO:0032511
GO:0032585
GO:0036258
GO:0039702
GO:0043162
GO:0043226
GO:0045296
GO:0046755
GO:0046761
GO:0051469
GO:0061024
GO:0061763
GO:0061952
GO:0070062
GO:0071222
GO:0071225
GO:0071985
GO:0090148
GO:0097352
GO:1901673
GO:1902774
GO:1904903
GO:1904930
HMNXSV003049949
ILMN_1732534
ILMN_2094166
PH_hs_0025016
PH_hs_0040375
TC09000139.hg
g7705488_3p_s_at
g7706273_3p_at
Participates
as a component of
Vps/Vta1 [cytosol] (Homo sapiens)
Inferred To
Chmp5 [cytosol]
(Mus musculus)
Chmp5 [cytosol]
(Rattus norvegicus)
CHMP5 [cytosol]
(Bos taurus)
CHMP5 [cytosol]
(Gallus gallus)
CHMP5 [cytosol]
(Schizosaccharomyces pombe)
CHMP5 [cytosol]
(Sus scrofa)
VPS60 [cytosol]
(Saccharomyces cerevisiae)
Vps60 [cytosol]
(Drosophila melanogaster)
chmp5 [cytosol]
(Dictyostelium discoideum)
chmp5 [cytosol]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENSP00000223500
,
ENST00000419016
,
ENST00000223500
,
ENSP00000442725
OpenTargets
ENSG00000086065
HPA
ENSG00000086065-CHMP5
PRO
Q9NZZ3
Pharos - Targets
Q9NZZ3
GlyGen
Q9NZZ3
PDB
2LXM
,
3ULY
,
3UM2
,
3UM0
,
4TXR
,
3UM1
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O95630 STAMBP
1
STAMBP [cytosol]
(R-HSA-5693063)
0.573
2
UniProt:Q9H444 CHMP4B
2
CHMP4B [cytosol]
(R-HSA-917708)
CHMP4B [endosome membrane]
(R-HSA-9631202)
0.547
4
UniProt:Q9Y3E7 CHMP3
2
CHMP3 [endosome membrane]
(R-HSA-9631191)
CHMP3 [cytosol]
(R-HSA-917722)
0.527
2
UniProt:O43633 CHMP2A
2
CHMP2A [cytosol]
(R-HSA-917734)
CHMP2A [endosome membrane]
(R-HSA-9631172)
0.527
2
UniProt:Q9HD42 CHMP1A
1
CHMP1A [cytosol]
(R-HSA-917721)
0.527
3
UniProt:Q96B97 SH3KBP1
3
SH3KBP1 [plasma membrane]
(R-HSA-182955)
SH3KBP1 [cytosol]
(R-HSA-182957)
Ub-SH3KBP1 [cytosol]
(R-HSA-182926)
0.527
2
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text