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p-S585-IL3RB:JAK2 [plasma membrane]
Stable Identifier
R-HSA-914173
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Homo sapiens)
14-3-3 zeta binding allows recruitment of PI3K (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(S585)-Bc [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:p(S585)-Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
p-S585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:pS585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
p-S585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
p-S585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta:p85-containing Class 1A PI3Ks [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(S585)-Bc [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:p(S585)-Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
p-S585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:pS585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
p-S585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
p-S585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
IL3RB is phosphorylated on Ser-585 (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(S585)-Bc [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:p(S585)-Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
p-S585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:pS585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
p-S585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
p-S585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
p-S585-IL3RB binds 14-3-3 proteins (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(S585)-Bc [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:p(S585)-Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
p-S585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:pS585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
p-S585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
p-S585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(S585)-Bc [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:p(S585)-Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
p-S585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:pS585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
p-S585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
p-S585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Participants
components
JAK2 [cytosol]
(Homo sapiens)
p-S585-CSF2RB [plasma membrane]
(Homo sapiens)
Participates
as a component of
GM-CSF:GM-CSF receptor alpha subunit:p(S585)-Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:pS585-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Inferred To
p-S585-IL3RB:JAK2 [plasma membrane]
(Bos taurus)
p-S585-IL3RB:JAK2 [plasma membrane]
(Canis familiaris)
p-S585-IL3RB:JAK2 [plasma membrane]
(Gallus gallus)
p-S585-IL3RB:JAK2 [plasma membrane]
(Mus musculus)
p-S585-IL3RB:JAK2 [plasma membrane]
(Rattus norvegicus)
p-S585-IL3RB:JAK2 [plasma membrane]
(Sus scrofa)
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