Reactome | IL3:IL3R active complex, inactive JAK2, p(Y593)-Bc [plasma membrane]

IL3:IL3R active complex, inactive JAK2, p(Y593)-Bc [plasma membrane]

Stable Identifier

R-HSA-914088

Type

Complex

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser

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Immune System (Homo sapiens)

- Cytokine Signaling in Immune system (Homo sapiens)
  - Signaling by Interleukins (Homo sapiens)
    - Interleukin-3, Interleukin-5 and GM-CSF signaling (Homo sapiens)
      - SHP1 and SHP2 dephosphorylate Y628 of IL3RB (Homo sapiens)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593)-Bc:SHP1, SHP2 [plasma membrane] (Homo sapiens)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593)-Bc [plasma membrane] (Homo sapiens)
        
        IL3:IL3R active complex, inactive JAK2, p(Y593)-Bc [plasma membrane] (Homo sapiens)

Participants

components

x 2 IL3RA:IL3:p(Y593)-IL3RB:JAK2 [plasma membrane] (Homo sapiens)

Participates

as a member of

High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593)-Bc [plasma membrane] (Homo sapiens)

Inferred To

IL3:IL3R active complex, inactive JAK2, p(Y593)-Bc [plasma membrane] (Bos taurus)

IL3:IL3R active complex, inactive JAK2, p(Y593)-Bc [plasma membrane] (Canis familiaris)

IL3:IL3R active complex, inactive JAK2, p(Y593)-Bc [plasma membrane] (Gallus gallus)

IL3:IL3R active complex, inactive JAK2, p(Y593)-Bc [plasma membrane] (Mus musculus)

IL3:IL3R active complex, inactive JAK2, p(Y593)-Bc [plasma membrane] (Rattus norvegicus)

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