SHP2 can recruit GRB2

Stable Identifier
R-HSA-914022
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
SHP2 can recruit GRB2
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
SHP2 can associate with GRB2 (Stein-Gerlach et al. 1995). IL-3 induces the phosphorylation of SHP2 and its association with GRB2 (Welham et al. 1994). SHP2 may act as a scaffold protein to recruit other signaling molecules, e.g. SHP2 was reported to link GRB2 to the receptor tyrosine kinase c-kit (Tauchi et al. 1994).
Participants
Input
Output
Participates
as an event of
Inferred From
Shp2 can recruit Grb2 (Mus musculus)
Authored
Ray, KP  (2010-05-17)
Reviewed
Hercus, TR  (2010-09-06)
Lopez, AF  (2010-09-06)
Created
Jupe, S  (2010-07-21)
Cite Us!