Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein

Stable Identifier
R-HSA-914008
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Golgi lumen
ReviewStatus
5/5
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Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein
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An unknown N-acetylglucosaminyltransferase mediates the transfer of GlcNAc to Tn antigens via an beta-1,6 linkage to create Core 6 mucins (Brockhausen et al. 2009).

Literature References
PubMed ID Title Journal Year
  Essentials of Glycobiology, 2nd edition

Brockhausen, I, Schachter, H, Stanley, P

  2009
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Orthologous Events
Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Bos taurus)
Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Caenorhabditis elegans)
Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Canis familiaris)
Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Danio rerio)
Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Dictyostelium discoideum)
Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Drosophila melanogaster)
Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Gallus gallus)
Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Mus musculus)
Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Plasmodium falciparum)
Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Rattus norvegicus)
Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Sus scrofa)
Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Xenopus tropicalis)
Authored
Jassal, B  (2010-07-19)
Reviewed
Ferrer, A  (2011-11-04)
Created
Jassal, B  (2010-07-21)
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