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High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane]
Stable Identifier
R-HSA-913458
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Homo sapiens)
Recruitment of SHC1 is mediated by Y593 of the common beta chain (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane] (Homo sapiens)
SHC1 bound to the common beta chain becomes tyrosine phosphorylated (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane] (Homo sapiens)
Participants
members
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane]
(Homo sapiens)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane]
(Homo sapiens)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane]
(Homo sapiens)
Participates
as an output of
Recruitment of SHC1 is mediated by Y593 of the common beta chain (Homo sapiens)
as an input of
SHC1 bound to the common beta chain becomes tyrosine phosphorylated (Homo sapiens)
Inferred To
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane]
(Bos taurus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane]
(Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane]
(Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane]
(Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane]
(Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane]
(Sus scrofa)
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