p-S585-IL3RB binds 14-3-3 proteins

Stable Identifier
R-HSA-912757
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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The common beta chain (Bc), binds 14-3-3 zeta at a site that requires phosphorylation of Serine 585 (Stomski et al. 1999). Bc modifications that prevent Ser-585 phosphorylation do not recruit 14-3-3 zeta (Guthridge et al. 2000).
Literature References
PubMed ID Title Journal Year
10477722 Identification of a 14-3-3 binding sequence in the common beta chain of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors that is serine-phosphorylated by GM-CSF

Bagley, CJ, Berndt, MC, Stomski, FC, Lopez, AF, Andrews, RK, Winnall, W, Dottore, M, Woodcock, J, Thomas, DT, Guthridge, MA

Blood 1999
Participants
Participates
Orthologous Events
Authored
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Created
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