p-S585-IL3RB binds 14-3-3 proteins

Stable Identifier
R-HSA-912757
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The common beta chain (Bc), binds 14-3-3 zeta at a site that requires phosphorylation of Serine 585 (Stomski et al. 1999). Bc modifications that prevent Ser-585 phosphorylation do not recruit 14-3-3 zeta (Guthridge et al. 2000).

Literature References
PubMed ID Title Journal Year
10477722 Identification of a 14-3-3 binding sequence in the common beta chain of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors that is serine-phosphorylated by GM-CSF

Stomski, FC, Dottore, M, Winnall, W, Guthridge, MA, Woodcock, J, Bagley, CJ, Thomas, DT, Andrews, RK, Berndt, MC, Lopez, AF

Blood 1999
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created