Cbl and Vav interact in thymocytes and peripheral T cells (Marengere et al. 1997). Cbl phosphorylated at Y700 binds Vav1 in 293T cells, leading to Vav ubiquitinylation and proteolytic degradation.
Penninger, JM, Kozieradzki, I, Marengère, LE, Veillette, A, Mak, TW, Mirtsos, C
Miura-Shimura, Y, Rottapel, R, Rao, NL, Duan, L, Reddi, AL, Band, H, Druker, BJ, Shimura, H, Tsygankov, A, Band, V
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