Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
ATP6V1G2 [cytosol]
Stable Identifier
R-HSA-912588
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to starvation (Homo sapiens)
Amino acids regulate mTORC1 (Homo sapiens)
RRAGA,B exchanges GDP for GTP (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
RRAGA,B hydrolyzes GTP (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
RRAGC,D exchanges GTP for GDP (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
RRAGC,D hydrolyzes GTP (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
mTORC1 binds RHEB:GTP (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
ROS and RNS production in phagocytes (Homo sapiens)
Intraphagosomal pH is lowered to 5 by V-ATPase (Homo sapiens)
V-ATPase [phagocytic vesicle membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by Insulin receptor (Homo sapiens)
Insulin receptor recycling (Homo sapiens)
ATP6AP1 binds V-ATPase (Homo sapiens)
V-ATPase [endosome membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
V-ATPase [endosome membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
Endosome acidification (Homo sapiens)
V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
V-ATPase [endosome membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
ATP6AP1 binds V-ATPase (Homo sapiens)
V-ATPase [endosome membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
V-ATPase [endosome membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
Iron uptake and transport (Homo sapiens)
Transferrin endocytosis and recycling (Homo sapiens)
ATP6AP1 binds V-ATPase (Homo sapiens)
V-ATPase [endosome membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
V-ATPase [endosome membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
Acidification of Tf:TfR1 containing endosome (Homo sapiens)
V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
V-ATPase [endosome membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O95670 ATP6V1G2
Gene Names
ATP6V1G2, ATP6G, ATP6G2, NG38
Chain
chain:1-118
Reference Genes
BioGPS Gene:534 ATP6V1G2
COSMIC (genes):ATP6V1G2 ATP6V1G2
CTD Gene:534 ATP6V1G2
dbSNP Gene:534 ATP6V1G2
ENSEMBL:ENSG00000206445.4 ATP6V1G2
ENSEMBL:ENSG00000213760 ATP6V1G2
ENSEMBL:ENSG00000213760.11 ATP6V1G2
ENSEMBL:ENSG00000226850.2 ATP6V1G2
ENSEMBL:ENSG00000227587.2 ATP6V1G2
ENSEMBL:ENSG00000230900.5 ATP6V1G2
ENSEMBL:ENSG00000234668.3 ATP6V1G2
ENSEMBL:ENSG00000234920.3 ATP6V1G2
HGNC:862 ATP6V1G2
KEGG Gene (Homo sapiens):534 ATP6V1G2
Monarch:534 ATP6V1G2
NCBI Gene:534 ATP6V1G2
OMIM:606853 ATP6V1G2
UCSC:O95670 ATP6V1G2
Reference Transcript
RefSeq:NM_138282.2 ATP6V1G2
RefSeq:NM_130463.3 ATP6V1G2
RefSeq:NM_001204078.1 ATP6V1G2
Other Identifiers
0003780494
0006020441
11734924_a_at
11755721_a_at
16655083
16655085
16655087
16655089
16655097
18670500
18670501
18670502
18670503
18670504
18670507
18670508
18670509
18670510
214762_PM_at
214762_at
2949077
2949078
2949079
2949080
2949081
2949082
2949084
2949085
2949086
2949087
33033_at
534
8124942
8178508
8179762
A_23_P500410
GE87270
GO:0000221
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005773
GO:0005829
GO:0006811
GO:0006914
GO:0008150
GO:0016020
GO:0016241
GO:0016471
GO:0016887
GO:0022857
GO:0030285
GO:0030665
GO:0031410
GO:0032991
GO:0042470
GO:0043226
GO:0046961
GO:0055085
GO:0140657
GO:1902600
HMNXSV003026228
Hs.249227.0.S1_3p_at
ILMN_1654541
ILMN_1674778
PH_hs_0013219
TC06004115.hg
TC6_cox_hap2000253.hg
TC6_dbb_hap3000232.hg
TC6_mann_hap4000201.hg
TC6_mcf_hap5000217.hg
TC6_qbl_hap6000231.hg
TC6_ssto_hap7000205.hg
Participates
as a member of
ATP6V1G [cytosol] (Homo sapiens)
Inferred To
wu:fa12a02 [cytosol]
(Danio rerio)
Atp6v1g2 [cytosol]
(Mus musculus)
Atp6v1g2 [cytosol]
(Rattus norvegicus)
atp6v1g1 [cytosol]
(Xenopus tropicalis)
ATP6V1G1 [cytosol]
(Canis familiaris)
vma10 [cytosol]
(Schizosaccharomyces pombe)
vha-10 [cytosol]
(Caenorhabditis elegans)
Vha13 [cytosol]
(Drosophila melanogaster)
VMA10 [cytosol]
(Saccharomyces cerevisiae)
atp6v1g [cytosol]
(Dictyostelium discoideum)
ATP6V1G2 [cytosol]
(Bos taurus)
ATP6V1G2 [cytosol]
(Plasmodium falciparum)
ATP6V1G2 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_569730.1
,
NP_612139.1
,
NP_001191007.1
Guide to Pharmacology - Targets
820
OpenTargets
ENSG00000213760
HPA
ENSG00000213760-ATP6V1G2
GeneCards
O95670
Ensembl
ENST00000447174
,
ENSP00000302194
,
ENSG00000230900
,
ENST00000454889
,
ENST00000434217
,
ENSG00000206445
,
ENSP00000406372
,
ENSP00000419698
,
ENST00000441959
,
ENSP00000409104
,
ENSP00000395436
,
ENSP00000365321
,
ENSG00000213760
,
ENSP00000372995
,
ENSP00000402430
,
ENST00000448779
,
ENST00000383503
,
ENSP00000406575
,
ENST00000421596
,
ENST00000449748
,
ENST00000454370
,
ENSG00000226850
,
ENSP00000408670
,
ENST00000452453
,
ENST00000443657
,
ENSG00000227587
,
ENSP00000413222
,
ENST00000303892
,
ENSP00000416031
,
ENST00000376151
,
ENSP00000403158
,
ENSP00000406668
,
ENST00000483251
,
ENSG00000234668
,
ENSG00000234920
,
ENSP00000406389
,
ENST00000444088
PRO
O95670
Pharos - Targets
O95670
HMDB Protein
HMDBP01274
© 2022
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
