Reactome | SYCP3 [nucleoplasm]

SYCP3 [nucleoplasm]

Stable Identifier

R-HSA-912329

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Synaptonemal complex protein 3, SYCP3_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P51451 BLK

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External Reference Information

External Reference

UniProt:Q8IZU3 SYCP3

Gene Names

SYCP3, SCP3

Chain

chain:1-236

Reference Genes

BioGPS Gene:50511 SYCP3

COSMIC (genes):SYCP3 SYCP3

CTD Gene:50511 SYCP3

dbSNP Gene:50511 SYCP3

ENSEMBL:ENSG00000139351 SYCP3

ENSEMBL_homo_sapiens_GENE:ENSG00000139351.15 SYCP3

HGNC:18130 SYCP3

KEGG Gene (Homo sapiens):50511 SYCP3

Monarch:50511 SYCP3

NCBI Gene:50511 SYCP3

OMIM:604759 SYCP3

UCSC:Q8IZU3 SYCP3

Reference Transcript

Other Identifiers

11727758_a_at

1553599_PM_a_at

1553599_a_at

16769144

3468081

3468082

3468084

3468085

3468089

3468090

3468092

3468094

3468099

3468100

3468101

3468102

50511

78060_at

7965800

A_23_P76374

GO:0000228

GO:0000775

GO:0000795

GO:0000800

GO:0003677

GO:0005515

GO:0005634

GO:0005694

GO:0006325

GO:0007049

GO:0007141

GO:0007286

GO:0022414

GO:0030154

GO:0035092

GO:0043226

GO:0048856

GO:0051301

GO:0051321

GO:0140013

HMNXSV003040441

Hs2.326538.1.S1_3p_s_at

ILMN_2123521

ILMN_2123525

TC12001879.hg

Participates

as an input of

Formation of axial/lateral elements of Synaptonemal Complex (Homo sapiens)

as a component of

Axial-Lateral Element of Synaptonemal Complex [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001171419.1, NP_710161.1, NP_001171420.1

OpenTargets

ENSG00000139351

HPA

ENSG00000139351-SYCP3

GeneCards

Q8IZU3

Ensembl

ENST00000392924, ENST00000392927, ENSP00000376658, ENST00000266743, ENSP00000266743, ENSG00000139351, ENSP00000376655

PRO

Q8IZU3

Pharos - Targets

Q8IZU3

Orphanet

23600

PDB

4CPC

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P51451 BLK	2	MyrG2-BLK [plasma membrane] (R-HSA-9606871) BLK [cytosol] (R-HSA-983580)	0.589	2
UniProt:Q9NWQ9 CN119			0.556	3
UniProt:Q9UBU9 NXF1	2	NXF1 [cytosol] (R-HSA-156481) NXF1 [nucleoplasm] (R-HSA-111690)	0.556	3
UniProt:Q16543 CDC37	1	CDC37 [cytosol] (R-HSA-1221609)	0.556	3
UniProt:P51587 BRCA2	20	BRCA2 D2983Ffs34 [cytosol] (R-HSA-9709538) BRCA2 K2555 [cytosol] (R-HSA-9711337) BRCA2 N2553Tfs95 [cytosol] (R-HSA-9712872) BRCA2 T2685Hfs9 [cytosol] (R-HSA-9712879) BRCA2 K2674Rfs2 [cytosol] (R-HSA-9712610) BRCA2 S3231 [cytosol] (R-HSA-9711458) BRCA2 I2675Dfs6 [cytosol] (R-HSA-9712869) BRCA2 R2625 [cytosol] (R-HSA-9711482) BRCA2 E3071* [cytosol] (R-HSA-9711354) BRCA2 V2716Wfs17 [cytosol] (R-HSA-9712761) BRCA2 W2586 [cytosol] (R-HSA-9711487) BRCA2 P2767Lfs10 [cytosol] (R-HSA-9712509) BRCA2 K3032 [cytosol] (R-HSA-9711485) BRCA2 S2835* [cytosol] (R-HSA-9711345) BRCA2 Y3006* [cytosol] (R-HSA-9711222) BRCA2 L2926* [cytosol] (R-HSA-9711348) BRCA2 R3128* [cytosol] (R-HSA-9711177) BRCA2 E2599* [cytosol] (R-HSA-9711304) BRCA2 E2571* [cytosol] (R-HSA-9711560) BRCA2 Y2977* [cytosol] (R-HSA-9711182)	0.463	2

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