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unfolded protein:(GlcNAc)2 (Man)8a [endoplasmic reticulum quality control compartment]
Stable Identifier
R-HSA-912285
Type
Complex
Species
Homo sapiens
Compartment
endoplasmic reticulum quality control compartment
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of glycosylation (Homo sapiens)
Diseases associated with N-glycosylation of proteins (Homo sapiens)
Defective MAN1B1 causes MRT15 (Homo sapiens)
Defective MAN1B1 does not hydrolyse a second 1,2-linked mannose (a branch) (Homo sapiens)
unfolded protein:(GlcNAc)2 (Man)8a [endoplasmic reticulum quality control compartment] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
N-glycan trimming in the ER and Calnexin/Calreticulin cycle (Homo sapiens)
Calnexin/calreticulin cycle (Homo sapiens)
ER Quality Control Compartment (ERQC) (Homo sapiens)
MAN1B1 hydrolyses 1,2-linked mannose (a branch) (Homo sapiens)
unfolded protein:(GlcNAc)2 (Man)8a [endoplasmic reticulum quality control compartment] (Homo sapiens)
MAN1B1 hydrolyses a second 1,2-linked mannose (a branch) (Homo sapiens)
unfolded protein:(GlcNAc)2 (Man)8a [endoplasmic reticulum quality control compartment] (Homo sapiens)
OS9:SEL1:ERAD E3 ligase:DERL2 ubiquitinates unfolded protein:(GlcNAc)2 (Man)9-5 (Homo sapiens)
Ub-unfolded protein:(GlcNAc)2 (Man)9-5 [endoplasmic reticulum quality control compartment] (Homo sapiens)
unfolded protein:(GlcNAc)2 (Man)9-5 [endoplasmic reticulum quality control compartment] (Homo sapiens)
unfolded protein:(GlcNAc)2 (Man)8a [endoplasmic reticulum quality control compartment] (Homo sapiens)
unfolded protein:(GlcNAc)2 (Man)9-5 [endoplasmic reticulum quality control compartment] (Homo sapiens)
unfolded protein:(GlcNAc)2 (Man)8a [endoplasmic reticulum quality control compartment] (Homo sapiens)
Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol (Homo sapiens)
Ub-unfolded protein:(GlcNAc)2 (Man)9-5 [endoplasmic reticulum quality control compartment] (Homo sapiens)
unfolded protein:(GlcNAc)2 (Man)9-5 [endoplasmic reticulum quality control compartment] (Homo sapiens)
unfolded protein:(GlcNAc)2 (Man)8a [endoplasmic reticulum quality control compartment] (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
Transport of glycoproteins with Man8 (or Man9) N-glycans to the Golgi (Homo sapiens)
Glycoproteins with Man8 N-glycans [endoplasmic reticulum quality control compartment] (Homo sapiens)
unfolded protein:(GlcNAc)2 (Man)8a [endoplasmic reticulum quality control compartment] (Homo sapiens)
Participants
components
(GlcNAc)2 (Man)8a [endoplasmic reticulum quality control compartment]
unfolded protein [endoplasmic reticulum quality control compartment]
(Homo sapiens)
Participates
as an input of
Defective MAN1B1 does not hydrolyse a second 1,2-linked mannose (a branch) (Homo sapiens)
MAN1B1 hydrolyses a second 1,2-linked mannose (a branch) (Homo sapiens)
as a member of
unfolded protein:(GlcNAc)2 (Man)9-5 [endoplasmic reticulum quality control compartment] (Homo sapiens)
Glycoproteins with Man8 N-glycans [endoplasmic reticulum quality control compartment] (Homo sapiens)
as an output of
MAN1B1 hydrolyses 1,2-linked mannose (a branch) (Homo sapiens)
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