Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
sABO-B [extracellular region]
Stable Identifier
R-HSA-9034076
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Soluble histo-blood group ABO system B transferase, BGAT_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Blood group systems biosynthesis (Homo sapiens)
ABO blood group biosynthesis (Homo sapiens)
sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen (Homo sapiens)
sABO-B:Mn2+ [extracellular region] (Homo sapiens)
sABO-B [extracellular region] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
2333095
Molecular genetic basis of the histo-blood group ABO system
Marken, J
,
White, T
,
Yamamoto, F
,
Hakomori, S
,
Clausen, H
Nature
1990
External Reference Information
External Reference
UniProt:P16442 ABO
Gene Names
ABO
Chain
chain:1-354, chain:54-354
Reference Genes
BioGPS Gene:28 ABO
COSMIC (genes):ABO ABO
CTD Gene:28 ABO
dbSNP Gene:28 ABO
HGNC:79 ABO
KEGG:hsa:28 ABO
Monarch:28 ABO
NCBI Gene:28 ABO
OMIM:110300 ABO
UCSC:P16442 ABO
Reference Transcript
RefSeq:NM_020469.2 ABO
Participates
as a component of
sABO-B:Mn2+ [extracellular region] (Homo sapiens)
Other forms of this molecule
ABO-B [Golgi membrane]
sABO-A [extracellular region]
ABO-A [Golgi membrane]
Inferred To
sABO-B [extracellular region]
(Bos taurus)
sABO-B [extracellular region]
(Canis familiaris)
sABO-B [extracellular region]
(Danio rerio)
sABO-B [extracellular region]
(Mus musculus)
sABO-B [extracellular region]
(Rattus norvegicus)
sABO-B [extracellular region]
(Xenopus tropicalis)
Homologues of sABO-B [extracellular region]
(Danio rerio)
Homologues of sABO-B [extracellular region]
(Rattus norvegicus)
Modified Residues
Name
L-arginine 176 replaced with glycine
Coordinate
176
PsiMod
L-arginine removal [MOD:01632]
A protein modification that effectively removes or replaces an L-arginine.
glycine residue [MOD:00017]
A protein modification that effectively converts a source amino acid residue to a glycine.
Name
glycine 235 replaced with L-serine
Coordinate
235
PsiMod
glycine removal [MOD:01638]
A protein modification that effectively removes or replaces an glycine.
L-serine residue [MOD:00025]
A protein modification that effectively converts a source amino acid residue to L-serine.
Name
L-leucine 266 replaced with L-methionine
Coordinate
266
PsiMod
L-methionine residue [MOD:00022]
A protein modification that effectively converts a source amino acid residue to L-methionine.
L-leucine removal [MOD:01641]
A protein modification that effectively removes or replaces an L-leucine.
Name
glycine 268 replaced with L-alanine
Coordinate
268
PsiMod
glycine removal [MOD:01638]
A protein modification that effectively removes or replaces an glycine.
L-alanine residue [MOD:00010]
A protein modification that effectively converts a source amino acid residue to an L-alanine.
Cross References
OpenTargets
ENSG00000175164
IntEnz
2.4.1.37
PRO
P16442
Pharos - Targets
P16442
GlyGen
P16442
HMDB Protein
HMDBP01100
PDB
1LZ0
,
2RJ1
,
5C36
,
5C4E
,
1LZI
,
2A8U
,
3I0I
,
3V0P
,
5C1H
,
6GWZ
,
3I0F
,
1ZI5
,
5CQM
,
3I0J
,
3SX7
,
5TJN
,
3I0D
,
5CQO
,
4FRO
,
1R7T
,
3U0Y
,
4Y64
,
5CMH
,
3SX3
,
2PGY
,
1ZJ2
,
4FRL
,
4GBP
,
5CMF
,
4KC4
,
4KXO
,
4FRA
,
3SXE
,
5M7B
,
5M7D
,
2RJ5
,
2RJ8
,
5C49
,
3ZGG
,
2Y7A
,
5C4B
,
2RIZ
,
2RJ0
,
3V0O
,
5C3A
,
3I0H
,
6GWY
,
6GX1
,
1XZ6
,
5TJL
,
1ZI4
,
5CQN
,
5BXC
,
3I0K
,
6BJI
,
4KC1
,
5TJO
,
1ZJP
,
1R82
,
1ZJ1
,
5CMI
,
4Y62
,
1WT1
,
3IOJ
,
1WT3
,
4FRP
,
3SXG
,
2PGV
,
2O1G
,
3SXC
,
6BJM
,
2RJ4
,
2RJ7
,
5C47
,
3ZGF
,
5C4C
,
2I7B
,
3V0N
,
1LZJ
,
5C38
,
2A8W
,
6GX0
,
5C3B
,
1ZHJ
,
5C3D
,
5C8R
,
3I0L
,
1ZI3
,
5TJK
,
3I0E
,
1WSZ
,
5CQP
,
4KC2
,
5C4F
,
1R7X
,
4FQW
,
4FRE
,
4C2S
,
1R81
,
4FRM
,
3U0X
,
5CMJ
,
3IOI
,
4FRB
,
1WT0
,
4FRQ
,
2O1F
,
6BJK
,
5M7A
,
1LZ7
,
5M7C
,
2RJ6
,
3SXA
,
6BJL
,
2RIX
,
3SX8
,
2RIY
,
5C4D
,
3V0M
,
5M79
,
5C1L
,
6GX2
,
3V0Q
,
5C1G
,
3I0G
,
5CQL
,
1ZIZ
,
1ZJ0
,
1R7V
,
1ZI1
,
1ZJO
,
1R7Y
,
3I0C
,
4FRD
,
3SX5
,
1R7U
,
5CMG
,
1R80
,
4Y63
,
1ZJ3
,
1WT2
,
2O1H
,
3IOH
,
3SXD
,
4FRH
,
6BJJ
,
3V0L
,
3SXB
,
2RJ9
,
2RIT
,
5C48
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text