Reactome | PHYH(1-338) [peroxisomal matrix]

PHYH(1-338) [peroxisomal matrix]

Stable Identifier

R-HSA-9033535

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

peroxisomal matrix

Synonyms

Phytanoyl-CoA dioxygenase, peroxisomal ecNumber1.14.11.18/ecNumber, PAHX_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O14832 PHYH

Gene Names

PHYH, PAHX

Chain

transit peptide:1-30, chain:31-338

Reference Genes

BioGPS Gene:5264 PHYH

COSMIC (genes):PHYH PHYH

CTD Gene:5264 PHYH

dbSNP Gene:5264 PHYH

ENSEMBL:ENSG00000107537 PHYH

ENSEMBL_homo_sapiens_GENE:ENSG00000107537.14 PHYH

HGNC:8940 PHYH

KEGG Gene (Homo sapiens):5264 PHYH

Monarch:5264 PHYH

NCBI Gene:5264 PHYH

OMIM:602026 PHYH

UCSC:O14832 PHYH

Reference Transcript

Other Identifiers

11729681_a_at

16711847

203335_PM_at

203335_at

32724_at

3278199

3278200

3278201

3278203

3278204

3278205

3278208

3278209

3278212

3278213

3278214

3278219

3278220

3278221

3278222

3278223

3278224

3278225

5264

7932094

A_23_P115919

GE58394

GO:0001561

GO:0003824

GO:0005515

GO:0005777

GO:0005782

GO:0005829

GO:0005929

GO:0006103

GO:0006629

GO:0006631

GO:0006720

GO:0008198

GO:0016491

GO:0019606

GO:0031406

GO:0031418

GO:0043226

GO:0046872

GO:0048244

GO:0051213

GO:0097089

GO:0097731

HMNXSV003036778

ILMN_1773073

ILMN_2282352

ILMN_2385566

PH_hs_0010355

TC10001048.hg

TC10002476.hg

g5453883_3p_at

Participates

as an input of

TYSND1 cleaves PHYH (Homo sapiens)

as a member of

Cargo proteins containing PTS2 [peroxisomal matrix] (Homo sapiens)

Other forms of this molecule

PHYH [peroxisomal matrix]

PHYH(1-338) [cytosol]

PHYH(1-30) [peroxisomal matrix]

Inferred To

PHYH [peroxisomal matrix] (Canis familiaris)

PHYH [peroxisomal matrix] (Sus scrofa)

PHYH(1-338) [peroxisomal matrix] (Bos taurus)

PHYH(1-338) [peroxisomal matrix] (Caenorhabditis elegans)

PHYH(1-338) [peroxisomal matrix] (Dictyostelium discoideum)

PHYH(1-338) [peroxisomal matrix] (Gallus gallus)

PHYH(1-338) [peroxisomal matrix] (Rattus norvegicus)

PHYH(1-338) [peroxisomal matrix] (Saccharomyces cerevisiae)

Phyh(1-338) [peroxisomal matrix] (Mus musculus)

phyh [peroxisomal matrix] (Xenopus tropicalis)

Cross References

RefSeq

NP_001310009.1, NP_001032626.1, NP_006205.1

OpenTargets

ENSG00000107537

IntEnz

1.14.11.18

HPA

ENSG00000107537-PHYH

GeneCards

O14832

Ensembl

ENSG00000107537, ENST00000396913, ENST00000263038, ENSP00000380121, ENSP00000263038

PRO

O14832

Pharos - Targets

O14832

Orphanet

15090

HMDB Protein

HMDBP00270

PDB

2A1X

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8IZU0 FAM9B			0.781	7
UniProt:Q9UNS2 COPS3	2	COPS3 [cytosol] (R-HSA-416973) COPS3 [nucleoplasm] (R-HSA-5697017)	0.675	4
UniProt:P43364 MAGAB			0.666	4
UniProt:A5PKX9 A5PKX9			0.556	3
UniProt:Q9UJX2 CDC23	2	CDC23 [cytosol] (R-HSA-174137) CDC23 [nucleoplasm] (R-HSA-174228)	0.556	3
UniProt:Q6PCB6 ABHD17C	1	ABHD17C [plasma membrane] (R-HSA-9647774)	0.556	3
UniProt:Q8IUI8 CRLF3			0.556	3
UniProt:O00463 TRAF5			0.556	3
UniProt:Q9ULX5 RN112			0.556	3
UniProt:Q3B7T1 EDRF1			0.556	3
UniProt:P29323-3 P293233			0.556	3
UniProt:Q6GQQ9-2 Q6GQQ92			0.556	3
UniProt:Q9UDY8-2 MALT1			0.556	3
UniProt:Q8N865 SMIP4			0.556	3
UniProt:O75925 PIAS1	1	PIAS1 [nucleoplasm] (R-HSA-877307)	0.556	3
UniProt:Q9UPM6 LHX6			0.556	3
UniProt:Q96FT7-4 ASIC4			0.556	3
UniProt:Q9Y2M5 KLHL20	1	KLHL20 [cytosol] (R-HSA-976032)	0.556	3
UniProt:Q86UV6-2 TRIM74			0.556	3
UniProt:Q5I0X4 CF226			0.527	3

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