Reactome | ECI2(39-394) [cytosol]

ECI2(39-394) [cytosol]

Stable Identifier

R-HSA-9033094

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

ECI2 isoform 2, Enoyl-CoA delta isomerase 2, mitochondrial ecNumber5.3.3.8/ecNumber, ECI2_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O75521-2 ECI2

Gene Names

ECI2, DRS1, HCA88, PECI

Other Identifiers

10455

11754652_a_at

17015240

218025_PM_s_at

218025_s_at

2939594

2939595

2939596

2939598

2939599

2939601

2939603

2939606

2939607

2939609

2939610

2939611

2939616

44706_at

8123695

A_23_P156852

GO:0000062

GO:0003824

GO:0004165

GO:0005515

GO:0005739

GO:0005777

GO:0005782

GO:0005829

GO:0006629

GO:0006635

GO:0008289

GO:0016020

GO:0016853

GO:0043226

GO:0043231

HMNXSV003031559

ILMN_1761131

ILMN_2384536

PH_hs_0001423

TC06003424.hg

g5174624_3p_s_at

Participates

as a member of

Cargo proteins containing PTS1 [cytosol] (Homo sapiens)

Other forms of this molecule

ECI2 [peroxisomal matrix]

Inferred To

eci2 [cytosol] (Xenopus tropicalis)

ECI2 [cytosol] (Bos taurus)

ECI2 [cytosol] (Canis familiaris)

ECI2 [cytosol] (Sus scrofa)

ECI2(39-394) [cytosol] (Caenorhabditis elegans)

ECI2(39-394) [cytosol] (Gallus gallus)

ECI2(39-394) [cytosol] (Mus musculus)

ECI2(39-394) [cytosol] (Rattus norvegicus)

ECI2(39-394) [cytosol] (Saccharomyces cerevisiae)

Dci [cytosol] (Drosophila melanogaster)

Cross References

RefSeq

NP_006108.2, NP_996667.2, NP_001159482.1

OpenTargets

ENSG00000198721

IntEnz

5.3.3.8

HPA

ENSG00000198721-ECI2

GeneCards

O75521

Ensembl

ENST00000380118, ENSP00000369461, ENSG00000198721

PRO

O75521

Pharos - Targets

O75521

PDB

2CQU, 2F6Q, 4U19, 4U18, 4U1A

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.615	18
UniProt:Q16659 MAPK6 gene	6	ub-MAPK6 [cytosol] (R-HSA-5687000) MAPK6 [cytosol] (R-HSA-5686979) p-S189 MAPK6 [cytosol] (R-HSA-5687019) p-S189 MAPK6 [nucleoplasm] (R-HSA-5687015) MAPK6 [nucleoplasm] (R-HSA-5692686) p-3S,T MAPK6 [nucleoplasm] (R-HSA-5692665)	0.527	2

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