Reactome | ECI2(39-394) [cytosol]

ECI2(39-394) [cytosol]

Stable Identifier

R-HSA-9033094

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

ECI2 isoform 2, Enoyl-CoA delta isomerase 2, mitochondrial ecNumber5.3.3.8/ecNumber, ECI2_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O75521-2 ECI2

Gene Names

ECI2, DRS1, HCA88, PECI

Other Identifiers

10455

11754652_a_at

11761967_a_at

17015240

218025_PM_s_at

218025_s_at

2939594

2939595

2939596

2939597

2939598

2939599

2939600

2939601

2939602

2939603

2939604

2939605

2939606

2939607

2939608

2939609

2939610

2939611

2939612

2939613

2939614

2939615

2939616

2939617

3203077

44706_at

8123695

A_23_P156852

GE61741

GO:0000062

GO:0004165

GO:0005515

GO:0005739

GO:0005777

GO:0005782

GO:0005829

GO:0006629

GO:0006635

GO:0008289

GO:0016020

GO:0016853

HMNXSV003031559

ILMN_1713833

ILMN_1761131

ILMN_2384536

PH_hs_0001423

RNA95697|RNS_779_124

TC06001235.hg

TC06003424.hg

g5174624_3p_s_at

Participates

as a member of

Cargo proteins containing PTS1 [cytosol] (Homo sapiens)

Other forms of this molecule

ECI2 [peroxisomal matrix]

Inferred To

eci2 [cytosol] (Xenopus tropicalis)

ECI2 [cytosol] (Bos taurus)

ECI2 [cytosol] (Canis familiaris)

ECI2 [cytosol] (Gallus gallus)

ECI2 [cytosol] (Sus scrofa)

ECI1 [cytosol] (Saccharomyces cerevisiae)

Eci2 [cytosol] (Mus musculus)

Eci2 [cytosol] (Rattus norvegicus)

Dci [cytosol] (Drosophila melanogaster)

Cross References

RefSeq

NP_006108.2, NP_001159482.1, NP_996667.2

ENSEMBL

ENSP00000369461, ENSG00000198721, ENST00000380118

OpenTargets

ENSG00000198721

IntEnz

5.3.3.8

GeneCards

ECI2

HPA

ENSG00000198721-ECI2

PRO

O75521

Pharos - Targets

O75521

GlyGen

O75521

HMDB Protein

HMDBP07372

PDB

4U18, 2CQU, 4U19, 4U1A, 2F6Q

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279)	0.615	18
UniProt:Q16659 MAPK6	6	p-3S,T MAPK6 [nucleoplasm] (R-HSA-5692665) MAPK6 [nucleoplasm] (R-HSA-5692686) p-S189 MAPK6 [nucleoplasm] (R-HSA-5687015) p-S189 MAPK6 [cytosol] (R-HSA-5687019) MAPK6 [cytosol] (R-HSA-5686979) ub-MAPK6 [cytosol] (R-HSA-5687000)	0.527	2