NTRK2-bound FYN autophosphorylates

Stable Identifier
R-HSA-9032532
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Upon binding to BDNF-activated NTRK2 (TRKB) receptor, autophosphorylation of FYN at tyrosine residue Y420 increases (Mizuno et al. 2003). The exact stoichiometry and involvement of other proteins is not known.

Participants
Participates
Catalyst Activity

protein tyrosine kinase activity of BDNF:p-5Y-NTRK2 homodimer:MyrG-FYN-1 [plasma membrane]

Inferred From
Authored
Reviewed
Created
Cite Us!