LTA4 translocates from neutrophil cytosol to platelet cytosol

Stable Identifier
R-HSA-9032036
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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LTA4 translocates from neutrophil cytosol to platelet cytosol
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Leukotriene A4 (LTA4), produced by 5-lipoxygenase (ALOX5) in neutrophils, can be taken up by platelets where it is acted upon by 12-lipoxygenase (ALOX12) to form lipoxins (Samuelsson et al. 1987). The mechanism of translocation is unknown.
Literature References
PubMed ID Title Journal Year
2820055 Leukotrienes and lipoxins: structures, biosynthesis, and biological effects

Dahlén, SE, Rouzer, CA, Serhan, CN, Lindgren, JA, Samuelsson, B

Science 1987
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Event Information
Go Biological Process
leukotriene transport (0071716)
Authored
Jassal, B  (2017-12-05)
Reviewed
Hansen, TV  (2018-02-21)
Created
Jassal, B  (2017-12-05)
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