RvT1-4 translocate from cytosol to extracellular region

Stable Identifier
R-HSA-9032021
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
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To produce their pro-resolving effects, 13(R)-resolvins RvT1-4 are released into the exudate of local inflammation sites (Dalli et al. 2015, Walker et al. 2017). The mechanism of translocation is unknown.

Literature References
PubMed ID Title Journal Year
28465323 13-Series resolvins mediate the leukocyte-platelet actions of atorvastatin and pravastatin in inflammatory arthritis

Walker, ME, Souza, PR, Colas, RA, Dalli, J

FASEB J. 2017
26236990 Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections

Dalli, J, Chiang, N, Serhan, CN

Nat. Med. 2015
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