Reactome | NTRK2-phosphorylated FRS2 binds PTPN11

NTRK2-phosphorylated FRS2 binds PTPN11

Stable Identifier

R-HSA-9031981

Type

Reaction [binding]

Species

Homo sapiens

Compartment

plasma membrane, cytosol

ReviewStatus

5/5

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Protein tyrosine phosphatase PTPN11 (SHP2) binds to FRS2 (also known as FRS2alpha or STN1) upon phosphorylation of FRS2 by activated NTRK2 (TRKB) (Easton et al. 2006).

Participants

Input