PD1n-3, PD2n-3 translocate from cytosol to extracellular region

Stable Identifier
R-HSA-9031896
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
cytosol, extracellular region
ReviewStatus
5/5
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PD1n-3, PD2n-3 translocate from cytosol to extracellular region
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To produce their pro-resolving effects, DPAn-3 derived protectins (PD1n-3 and PD2n-3) are released into the exudate of local inflammation sites (Dalli et al. 2013, Vik et al. 2017). The mechanism of translocation is unknown.

Literature References
PubMed ID Title Journal Year
23736886 Novel n-3 immunoresolvents: structures and actions

Serhan, CN, Colas, RA, Dalli, J

Sci Rep 2013
28408222 Recent advances in the chemistry and biology of anti-inflammatory and specialized pro-resolving mediators biosynthesized from n-3 docosapentaenoic acid

Hansen, TV, Vik, A, Dalli, J

Bioorg. Med. Chem. Lett. 2017
Participants
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Output
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Authored
Jassal, B  (2017-12-04)
Reviewed
Hansen, TV  (2018-02-21)
Created
Jassal, B  (2017-12-04)
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