DPAn-3 maresins translocate from cytosol to extracellular region

Stable Identifier
R-HSA-9031894
Type
Reaction [uncertain]
Species
Homo sapiens
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To produce their pro-resolving effects, DPAn-3 derived maresins (MaR1n-3DPA, MaR2n-3DPA and MaR3n-3DPA) are released into the exudate of local inflammation sites (Dalli et al. 2013, Vik et al. 2017). The mechanism of translocation is unknown.

Literature References
PubMed ID Title Journal Year
28408222 Recent advances in the chemistry and biology of anti-inflammatory and specialized pro-resolving mediators biosynthesized from n-3 docosapentaenoic acid

Vik, A, Dalli, J, Hansen, TV

Bioorg. Med. Chem. Lett. 2017
23736886 Novel n-3 immunoresolvents: structures and actions

Dalli, J, Colas, RA, Serhan, CN

Sci Rep 2013
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