Protectins translocate from cytosol to extracellular region

Stable Identifier
R-HSA-9031807
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol, extracellular region
ReviewStatus
5/5
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Protectins translocate from cytosol to extracellular region
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To produce their pro-resolving effects, protectins PDX, (N)PD1, AT-(N)PD1 and 22-OH-(N)PD1 are released into the exudate of local inflammation sites (Serhan et al. 2014, 2015). The mechanism of translocation is unknown.
Literature References
PubMed ID Title Journal Year
25359497 Lipid mediators in the resolution of inflammation

Serhan, CN, Chiang, N, Dalli, J, Levy, BD

Cold Spring Harb Perspect Biol 2014
25139562 Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome

Serhan, CN, Dalli, J, Colas, RA, Winkler, JW, Chiang, N

Biochim. Biophys. Acta 2015
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Event Information
Go Biological Process
icosanoid secretion (0032309)
Authored
Jassal, B  (2017-12-04)
Reviewed
Hansen, TV  (2018-02-21)
Created
Jassal, B  (2017-12-04)
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