An unidentified hydroperoxy reductase reduces 14(S)-hydroperoxy-docosahexaenoic acid (14(S)-Hp-DHA) to form 14(S)-hydroxy-docosahexaenoic acid (14(S)-HDHA), the precursor for the formation of maresin-like mediator Mar-L1 (Hong et al. 2014) and 14(S),21-dihydroxy-docosahexaenoic acids (Lu et al. 2010).
Alapure, BV, Lu, Y, Tian, H, Bunnell, BA, Wang, Q, Hong, S, Laborde, JM
oxidoreductase activity of Hydroperoxy reductase [cytosol]
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