GGT hydrolyses RCTR2 to RCTR3

Stable Identifier
R-HSA-9026916
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Presumably following a similar synthesis route to protectin conjugate in tissue regeneration 3 (PCTR3), resolvin conjugate in tissue regeneration 2 (RCTR2) could be hydrolysed to RCTR3 (8-cysteinyl, 7,17-dihydroxy-docosahexaenoic acid) by the actions of a glutathione transferase (GGT) (Dalli et al. 2015).

Literature References
PubMed ID Title Journal Year
25713027 Novel proresolving and tissue-regenerative resolvin and protectin sulfido-conjugated pathways

Dalli, J, Ramon, S, Norris, PC, Colas, RA, Serhan, CN

FASEB J. 2015
Participants
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Catalyst Activity
Catalyst Activity
Title
glutathione hydrolase activity of GGT [cytosol]
Physical Entity
Activity
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Created