In neutrophils, 5-lipoxygenase (ALOX5) oxidises 13(R)-hydroxy-docosapentaenoic acid (13(R)-DPAn-3) to the 13(R)-resolvins RvT1-4 (7,13,20-trihydroxy-docosapentaenoic acid, 7,12,13-trihydroxy-docosapentaenoic acid, 7,8,13-trihydroxy-docosapentaenoic acid and 7,13-dihydroxy-docosapentaenoic acid respectively) (Dalli et al. 2015, Primdahl et al. 2016). They were all shown to posses anti-inflammatory and proresolving activities (Dalli et al. 2015). Recently, RvTs have been shown to mediate the proresolving actions of several statins in mice with inflammatory arthritis (Walker et al. 2017).