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EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:CRKL:RAPGEF1 [plasma membrane]
Stable Identifier
R-HSA-9024721
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Erythropoietin (Homo sapiens)
Erythropoietin activates RAS (Homo sapiens)
EPO:p-EPOR:p-JAK2:LYN:IRS2 binds CRKL:RAPGEF1 (Homo sapiens)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:CRKL:RAPGEF1 [plasma membrane] (Homo sapiens)
LYN phosphorylates CRKL in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:CRKL:RAPGEF1 (Homo sapiens)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:CRKL:RAPGEF1 [plasma membrane] (Homo sapiens)
Participants
components
CRKL:RAPGEF1 [cytosol]
(Homo sapiens)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2 [plasma membrane]
(Homo sapiens)
Participates
as an output of
EPO:p-EPOR:p-JAK2:LYN:IRS2 binds CRKL:RAPGEF1 (Homo sapiens)
as an input of
LYN phosphorylates CRKL in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:CRKL:RAPGEF1 (Homo sapiens)
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