NCOA1 recruits EP300 to TGFA promoter

Stable Identifier
Reaction [binding]
Homo sapiens
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Estrogen-dependent interaction between NCOA1 and EP300 recruits EP300 to the TGFA promoter (Halachmi et al, 1994; Cavaillès et al, 1994; Harnstein et al, 2001). NCOA1 and EP300 contribute to active chromatin structures through their coactivator and histone acetyltransferase activity (reviewed in Xu et al, 2007; Arnal et al, 2017).
Literature References
PubMed ID Title Journal Year
28539435 Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications

Katzenellenbogen, B, Chambon, P, Flouriot, G, Métivier, R, Henrion, D, Katzenellenbogen, J, Arnal, JF, Lenfant, F, Gourdy, P, Fontaine, C, Adlanmerini, M

Physiol. Rev. 2017
7937828 Interaction of proteins with transcriptionally active estrogen receptors

Parker, MG, Dauvois, S, Danielian, PS, Cavaillès, V

Proc. Natl. Acad. Sci. U.S.A. 1994
8197458 Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription

Halachmi, S, Brown, M, Martin, G, Marden, E, MacKay, H, Abbondanza, C

Science 1994
14631847 Acetylation and methylation in nuclear receptor gene activation

Xu, W, Evans, RM, Cho, H

Meth. Enzymol. 2003
8876171 p300 is a component of an estrogen receptor coactivator complex

Brown, M, Hanstein, B, DiRenzo, J, Eckner, R, Searcy, B, Kurokawa, R, Liu, H, Halachmi, S

Proc. Natl. Acad. Sci. U.S.A. 1996
Orthologous Events
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