DLL1 gene expression is inhibited by MECP2

Stable Identifier
R-HSA-9023351
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Based on studies in mice, increased MECP2 occupancy of the DLL1 gene promoter, encoding NOTCH ligand Delta 1, correlates with decreased transcription of DLL1. MECP2 therefore inhibits DLL1 transcription (Li et al. 2014).

Participants
Participant Of
This event is regulated
Inferred From
Authored
Reviewed
Created