SGK1 gene expression is inhibited by MECP2

Stable Identifier
R-HSA-9022764
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
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SGK1 gene expression is inhibited by MECP2
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Based on studies in mice, MECP2 directly inhibits transcription of the SGK1 gene encoding serum/glucocorticoid-regulated kinase 1. Sgk1 level is increased in Mecp2 null mice (Nuber et al. 2005).
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Input
Output
Participates
as an event of
This event is regulated
Negatively by
Regulator
MECP2:SGK1 gene [nucleoplasm] (Homo sapiens)
Active Unit
MECP2 [nucleoplasm]
Inferred From
Sgk1 gene expression is inhibited by Mecp2 (Mus musculus)
Authored
Orlic-Milacic, M  (2017-10-02)
Reviewed
Krishnaraj, R  (2018-08-07)
Christodoulou, J  (2018-08-07)
Created
Orlic-Milacic, M  (2017-09-25)
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