MECP2 regulates transcription factors

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Homo sapiens
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MECP2 regulates transcription of several transcription factors involved in functioning of the nervous system, such as CREB1, MEF2C, RBFOX1 (Chahrour et al. 2008) and PPARG (Mann et al. 2010, Joss Moore et al. 2011).

Literature References
PubMed ID Title Journal Year
19843474 MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis

Mann, J, Chu, DC, Maxwell, A, Oakley, F, Zhu, NL, Tsukamoto, H, Mann, DA

Gastroenterology 2010
21425435 IUGR differentially alters MeCP2 expression and H3K9Me3 of the PPARĪ³ gene in male and female rat lungs during alveolarization

Joss-Moore, LA, Wang, Y, Ogata, EM, Sainz, AJ, Yu, X, Callaway, CW, McKnight, RA, Albertine, KH, Lane, RH

Birth Defects Res. Part A Clin. Mol. Teratol. 2011
18511691 MeCP2, a key contributor to neurological disease, activates and represses transcription

Chahrour, M, Jung, SY, Shaw, C, Zhou, X, Wong, ST, Qin, J, Zoghbi, HY

Science 2008
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