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SIN3A:HDAC1 homodimer [nucleoplasm]
Stable Identifier
R-HSA-9022430
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Disorders of Developmental Biology (Homo sapiens)
Disorders of Nervous System Development (Homo sapiens)
Pervasive developmental disorders (Homo sapiens)
Loss of function of MECP2 in Rett syndrome (Homo sapiens)
Loss of MECP2 binding ability to 5mC-DNA (Homo sapiens)
MECP2 T158A:SIN3A complex does not bind BDNF gene promoter (Homo sapiens)
MECP2 T158A:SIN3A:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1 homodimer [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
FOXO-mediated transcription (Homo sapiens)
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes (Homo sapiens)
FOXO1 and SIN3A:HDAC complex bind GCK gene promoter (Homo sapiens)
FOXO1:SIN3A:HDAC1.HDAC2 dimers:GCK gene [nucleoplasm] (Homo sapiens)
FOXO1:SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1 homodimer [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1 homodimer [nucleoplasm] (Homo sapiens)
GCK gene expression is inhibited by FOXO1, SIN3A and HDACs (Homo sapiens)
FOXO1:SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1 homodimer [nucleoplasm] (Homo sapiens)
FOXO1:SIN3A:HDAC1.HDAC2 dimers:GCK gene [nucleoplasm] (Homo sapiens)
FOXO1:SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1 homodimer [nucleoplasm] (Homo sapiens)
Transcriptional Regulation by MECP2 (Homo sapiens)
MECP2 regulates transcription of neuronal ligands (Homo sapiens)
BDNF gene transcription (Homo sapiens)
MECP2:SIN3A:HDAC1:BDNF gene [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1 homodimer [nucleoplasm] (Homo sapiens)
MECP2:SIN3A complex binds the promoter of the BDNF gene (Homo sapiens)
MECP2:SIN3A:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1 homodimer [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:BDNF gene [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1 homodimer [nucleoplasm] (Homo sapiens)
Regulation of MECP2 expression and activity (Homo sapiens)
MECP2 binds the SIN3A co-repressor complex (Homo sapiens)
MECP2:SIN3A:HDAC1,HDAC2 [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1 homodimer [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1 homodimer [nucleoplasm] (Homo sapiens)
Participants
components
HDAC1 homodimer [nucleoplasm]
(Homo sapiens)
SIN3A [nucleoplasm]
(Homo sapiens)
Participates
as a component of
MECP2 T158A:SIN3A:HDAC1 [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1 [nucleoplasm] (Homo sapiens)
as a member of
SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
Inferred To
SIN3A:HDAC1 homodimer [nucleoplasm]
(Bos taurus)
SIN3A:HDAC1 homodimer [nucleoplasm]
(Caenorhabditis elegans)
SIN3A:HDAC1 homodimer [nucleoplasm]
(Canis familiaris)
SIN3A:HDAC1 homodimer [nucleoplasm]
(Dictyostelium discoideum)
SIN3A:HDAC1 homodimer [nucleoplasm]
(Drosophila melanogaster)
SIN3A:HDAC1 homodimer [nucleoplasm]
(Gallus gallus)
SIN3A:HDAC1 homodimer [nucleoplasm]
(Mus musculus)
SIN3A:HDAC1 homodimer [nucleoplasm]
(Rattus norvegicus)
SIN3A:HDAC1 homodimer [nucleoplasm]
(Saccharomyces cerevisiae)
SIN3A:HDAC1 homodimer [nucleoplasm]
(Schizosaccharomyces pombe)
SIN3A:HDAC1 homodimer [nucleoplasm]
(Sus scrofa)
SIN3A:HDAC1 homodimer [nucleoplasm]
(Xenopus tropicalis)
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