Based on studies in mice, transcription of the SLC2A3 (GLUT3) gene, encoding solute carrier family 2, facilitated glucose transporter member 3, is directly stimulated by the complex of MECP2 and CREB1. In the mouse brain, expression of the Slc2a3 gene is developmentally regulated, peaking at postnatal day 14, which correlates with hypermethylation of the 5' flanking region CpG island (Chen et al. 2013).
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