MECP2:CREB1 complex binds SLC2A3 gene

Stable Identifier
R-HSA-9022175
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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MECP2:CREB1 complex binds SLC2A3 gene
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Based on studies in mice, the complex of MECP2 and CREB1 binds to a hypermethylated CpG island in the 5' flanking region of the SLC2A3 (GLUT3) gene, encoding solute carrier family 2, facilitated glucose transporter member 3 (Chen et al. 2013).

Literature References
PubMed ID Title Journal Year
23493374 Creb1-Mecp2-(m)CpG complex transactivates postnatal murine neuronal glucose transporter isoform 3 expression

Thamotharan, S, Chen, Y, Devaskar, SU, Shin, BC

Endocrinology 2013
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Output
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as an event of
Inferred From
Mecp2:Creb1 binds Slc2a3 gene (Mus musculus)
Authored
Orlic-Milacic, M  (2017-10-02)
Reviewed
Krishnaraj, R  (2018-08-07)
Christodoulou, J  (2018-08-07)
Created
Orlic-Milacic, M  (2017-09-21)
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