MECP2:CREB1 complex binds SLC2A3 gene

Stable Identifier
R-HSA-9022175
Type
Reaction [binding]
Species
Homo sapiens
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Based on studies in mice, the complex of MECP2 and CREB1 binds to a hypermethylated CpG island in the 5' flanking region of the SLC2A3 (GLUT3) gene, encoding solute carrier family 2, facilitated glucose transporter member 3 (Chen et al. 2013).

Literature References
PubMed ID Title Journal Year
23493374 Creb1-Mecp2-(m)CpG complex transactivates postnatal murine neuronal glucose transporter isoform 3 expression

Chen, Y, Shin, BC, Thamotharan, S, Devaskar, SU

Endocrinology 2013
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