PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes

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R-HSA-9021450
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Reaction [omitted]
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Homo sapiens
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PLXND1 gene transcription is stimulated by NOTCH1 and NOTCH3 coactivator complexes. PLXND1 encodes the semaphorin receptor Plexin-D1, involved in neuronal migration as well as cancer cell invasiveness (Rehman et al. 2016).

Literature References
PubMed ID Title Journal Year
27749937 PlexinD1 Is a Novel Transcriptional Target and Effector of Notch Signaling in Cancer Cells

Rehman, M, Gurrapu, S, Cagnoni, G, Capparuccia, L, Tamagnone, L

PLoS ONE 2016
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