ELF3 binds NOTCH3 gene promoter

Stable Identifier
R-HSA-9021364
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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ELF3 binds NOTCH3 gene promoter
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ELF3, phosphorylated by PRKCI (protein kinase C iota) on serine residue S68, binds multiple ELF3-binding sites in the NOTCH3 gene promoter (Ali et al. 2016).

Literature References
PubMed ID Title Journal Year
26977885 Protein Kinase Cι Drives a NOTCH3-dependent Stem-like Phenotype in Mutant KRAS Lung Adenocarcinoma

Jamieson, L, Justilien, V, Murray, NR, Ali, SA, Fields, AP

Cancer Cell 2016
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Output
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Event Information
Go Biological Process
positive regulation of Notch signaling pathway (0045747)
Authored
Orlic-Milacic, M  (2017-09-20)
Reviewed
Haw, R  (2017-10-30)
Created
Orlic-Milacic, M  (2017-09-18)
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