ELF3 binds NOTCH3 gene promoter

Stable Identifier
R-HSA-9021364
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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ELF3 binds NOTCH3 gene promoter
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ELF3, phosphorylated by PRKCI (protein kinase C iota) on serine residue S68, binds multiple ELF3-binding sites in the NOTCH3 gene promoter (Ali et al. 2016).

Literature References
PubMed ID Title Journal Year
26977885 Protein Kinase Cι Drives a NOTCH3-dependent Stem-like Phenotype in Mutant KRAS Lung Adenocarcinoma

Ali, SA, Justilien, V, Jamieson, L, Murray, NR, Fields, AP

Cancer Cell 2016
Participants
Input
Output
Participant Of
hasEvent
Event Information
Go Biological Process
positive regulation of Notch signaling pathway (0045747)
Authored
Orlic-Milacic, M  (2017-09-20)
Reviewed
Haw, R  (2017-10-30)
Created
Orlic-Milacic, M  (2017-09-18)